Yeast is arguably the most important industrial microorganism in the world, playing a critical role in the fermentation of food and beverage products, as well as cellular factory for production of biofuels, chemicals, and pharmaceuticals. In order to produce such a range of products efficiently and economically, specialized yeast must be optimized for each task. […]

The goal of this research is to improve breast cancer local control and reduce treatment side effects by demonstrating that a new cold plasma technology, which generates locally specific reactive oxygen species, has an additive positive treatment impact when combined with conventional radiotherapy. This project has the potential to enable a Canadian technology, to become […]

The goal of this project is to evaluate the data quality of the citizen science Golden Eagle count data collected by the Rocky Mountain Eagle Research Foundation and to determine the population trend over 25 years. Since 1993 they have collected data, consisting of daily raptor migration counts in the Fall and Spring seasons. It […]

The aim of this project is therefore to develop polymer-based formulations of bacteriophages to combat microbial infections. Bacteriophages are a class of viruses specific to bacteria that are not subject to antibiotic resistance and are the most prevalent organisms of the human virome, and therefore safe.2 We will use different polymer compositions and blends to […]

This proposal presents two parallel research projects to develop pattern recognition algorithms using a relatively new technology, Electrovestibulography (EVestGTM)1 for objectively and accurately effect of confounding depression on concussion both when used as a diagnostic tool and also as a treatment recovery tool. EVestG signals are recorded painlessly and non-invasively from the external ear in […]

Infections acquired through long-term catheter use are a major problem for nearly 20% of all patients. This project seeks to apply Econous Systems’ anti-fouling MEG-OH coating to biomedical plastic catheters to see if they prevent the 3 most common microbes: E. coli, C. Albicans and S. Aureus, from growing. This will initially involve in vitro […]

One of the most promising strategies for discovering our future medications is via fragment-based lead discovery (FBLD). FBLD involves the screening of libraries of small molecules to first identify weak binders to essential target proteins of diseases. These binders are then synthetically matured to larger, more potent inhibitors/leads via medicinal chemistry design efforts. However, there […]

Acute myocardial infarction (commonly known as a heart attack) is a major disease of the cardiovascular system and a leading cause of death and hospitalization in North America. It results in 7.4 million deaths globally per annum. Current clinical medications only prevent the disease but cannot cure it after a heart attack occurs. Scientific evidence […]

The aim of the internship program is to develop a rehabilitation harness for horses and study its use together with a computerized lift system designed for rehabilitation of injured horses. Measurements used to direct harness design and rehabilitation protocols include movement analysis of the horses, physiological measurements and analysis of behaviour. The lift system was […]

Heavy pesticide and antibiotic use are prevalent in modern agriculture and is an essential requirement to feed the ever-increasing human population. Their increased use, however, has also resulted in a loss of ecological biodiversity, environmental contamination, emerging pesticide/antibiotic resistance and is an economic burden to farmers, especially in low income nations. The research proposed aims […]

Wetlands provide critical habitat and valuable ecosystem services. Land use conversion in Ontario, however, has led to substantial wetland loss. The restoration of wetlands on agricultural properties has the potential to offset wetland loss, yet these wetlands are also susceptible to contamination by pesticides. Our research will therefore establish: (1) to what degree restored wetlands […]

The City of Saint John has been facing the generational poverty challenge for decades. The poverty rate in this city is 19.7%, which is more than five percent higher than the average rate of the province (14.5%) and the country (14.4%) [1]. Having access to real-time data of low-income families and people suffering from poverty […]