Validation of novel neurofeedback training engine for improving brain health in aging and neurodevelopmental disorders

Memory impairment is the most common cognitive complaint among older adults. On the other side of the developmental spectrum, young adults that have been diagnosed with Autism Spectrum Disorders (ASD) have difficulty adapting flexibly to changing social circumstances. These memory and social deficits disrupt every day living. At present, promising interventions based on research using […]

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Validation of novel neurofeedback training engine for improving brain health in aging and neurodevelopmental disorders – Year two

Memory impairment is the most common complaint associated with aging. Promising interventions based on research are generally reserved for clinical settings. Technological advancement has now made it possible to administer neurofeedback, an established technique for self-regulating brain waves, using portable technology. xSensa Labs, the partner organization, has developed a digital solution that translates research protocols […]

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Multi-level modeling methodologies for aircraft thermal architecture optimization

The proposed project will contribute to Bombardier’s research initiative “Virtual Aircraft” with the overall objective to improve modeling and simulation throughout the development process to enable innovation and reduce development risk through extensive design space exploration. The objective is to develop models of thermal aspects, traditionally investigated later in the design, when the aircraft architecture […]

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Multi-level modeling methodologies for aircraft thermal architecture optimization – Year two

The proposed project will contribute to Bombardier’s research initiative “Virtual Aircraft” with the overall objective to improve modelling and simulation throughout the development process to enable innovation and reduce development risk to extensive design space exploration. The objective of the project is to develop models of thermal aspects, traditionally investigated later in the design, when […]

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Self-powered microchips for rapid diagnosis and severity determination of urinary tract infections

Children presenting a fever without known sources are usually checked for bacterial urinary tract infection (UTI) which, in its more complicated forms, can result in permanent kidney damage. The gold standard conventional tests to diagnose complicated urinary tract infections are urine culture and kidney imaging with a radioactive tracer. However, these tests are lengthy (urine […]

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Development of miniature fluorescence microscope with optogenetically synchronized patterned illumination

Myriad of complex interactions from molecular to system level underlie the functioning of the brain, and their thorough understanding is crucial for ultimate experimental goals of neuroscience. Recent breakthroughs in optogenetics allow controling the activity of small groups and even single neurons while recording their responses with minimal effect on natural biological processes. Currently though, […]

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Development of miniature fluorescence microscope with optogenetically synchronized patterned illumination – Year two

We propose development of miniature fluorescent microscope with flexible spatiotemporal photostimulation patterns of ensembles of neurons in freely behaving animals.For precision and targeted photostimulation of light-activated proteins (opsins), the light beam from high power incoherent light source will be shaped by user-controlled digital micromirror device (DMD). The light patterns formed by DMD will be sent […]

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Multi-objective Topology Optimization of an Automotive Cradle

A cradle is a separate structure from automotive chassis, which is used to support the powertrain and suspension system. With the application of cradle structure, the noise and vibration transmitted to passengers will be reduced and the stiffness of attachments will be increased. In other words, the riding comfort and the product reliability are improved. […]

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Determination of active surface area, gas permeability, and mass transport resistance in fuel cell catalyst layers

Gas transport in polymer electrolyte membrane fuel cells is of increasing interest since low gas crossover is desired in the membrane, however high gas transport is desired in the catalyst layer where ionomer is present (and is typically similar in chemical structure to the membrane). This project will investigate the permeability of oxygen, nitrogen, and […]

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Phase II: Genomics and Lipid Studies for Flavour Selection in Pork

The hog industry in Manitoba is a very efficient means of converting grains and pulses into high quality protein. Fresh pork is a healthy and nutritious source of protein, yet demand remains static. One of the main reasons cited by consumers for not choosing pork is the absence of good taste in modern pork. The […]

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