Investigation of the Health Benefits of a Novel Sourdough Fermented Pasta

There are several factors driving an insatiable market for natural health products in the Canadian marketplace, including growing consumer interest in food-health relationships, rising healthcare costs and an aging population. One growing natural health food niche includes fermented foods that are becoming increasingly recognized for their health benefits. This project aims to explore the benefits […]

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Using Engaged Philosophical Inquiry in Drug Education – Year Two

Research has shown that “no use” drug education programs, with the objective of scaring or shaming youth into abstinence, have not been effective in addressing problematic substance use. The ineffectiveness of such scare tactic approaches has led program developers to focus on prevention and harm reduction associated with drug use, or in general, health literacy […]

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Respirable Crystalline Silica: A Risk Assessment Tool for the Construction Sector

Silica is a known lung carcinogen and causes silicosis, an irreversible fibrotic lung disease. RCS is a major problem in the construction sector because of the high content of silica in construction materials. New tools are needed to help the construction industry in recognition, evaluation and control of RCS. The intern will develop an on-line […]

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Assessment of Tissue Viability in the Lower Extremity of Diabetic Patients

In Canada, people with diabetes are 20x more likely to have an amputation of their lower limb than the general population. Having a diabetic foot ulcer (DFU) increases the risk of amputation by 50%. Early assessment and treatment of a patient’s DFU can prevent amputation, but patients with diabetes often lose sensation in their limbs, […]

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Internet of Smarter Things: A Data-driven Perspective

All over the world, sensors, smart objects, and other devices are connecting through the reach and power of the Internet. And they are dynamically generating, analyzing, and communicating intelligence to increase operational efficiency, power new business models, and improve quality of life. Connecting the unconnected is the Internet of Things (IoT). The project would focus […]

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Computational Approaches for Characterizing Non-canonical Tandem Mass Spectra

Extensive research has been conducted for the computational analysis of mass spectrometry based proteomics data, however most of the traditional computational approaches take the assumption that the acquired spectra are generated from the fragmentation of a single precursor and the peptide is simply a linear sequence of amino acid residues. This ubiquitous assumption is impeding […]

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Development of a novel robust clone for the manufacturing of AVID100 biosimilar

AVID100 is an antibody-drug conjugate (ADC) against a validated cancer target that is undergoing IND-enabling studies. Phase I clinical trials are scheduled for late 2016. The monoclonal antibody (mAb) portion of the ADC is currently manufactured using a recombinant CHO clone that fails to meet industrial production yield standards. In order to support clinical phases […]

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