Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

31132 Completed Projects

2940
AB
5159
BC
837
MB
685
NL
882
SK
9291
ON
9695
QC
97
PE
601
NB
1161
NS

Projects by Category

Harnessing the mutation-reactive T-cell response against metastatic colorectal cancer

Colorectal cancer remains within the three most lethal cancers, largely due to the inevitable development of resistance to chemotherapy. Recent breakthroughs demonstrate that cancer immunotherapy can be highly effective in patients with skin cancer using T cells from the human immune system to fight off cancer. Our laboratory has found that T cells can recognize cancer as foreign because genes in cancer cells undergo mutations. We now propose to test if immunotherapy with T cells targeting cancer mutations can be developed against colorectal cancer. To this end, we will use samples from patients treated at the CHUM and perform studies with mutation-reactive T cells in a mouse model. Investigating ways to extend the benefits of immunotherapy to a common cancer will position the applicant as an expert in the field, and the Institut du Cancer de Montreal as a leader in the development of novel cancer therapeutics.

View Full Project Description
Faculty Supervisor:

Simon Turcotte

Student:

Partner:

Institut du cancer de Montréal

Discipline:

Life Sciences

Sector:

Other services (except public administration); Professional, scientific and technical services

University:

Université de Montréal

Program:

Elevate

Secondary cataract assessment in eyes implanted with different intraocular lenses

Cataract surgery is one of the most common surgeries performed worldwide. The incidence of posterior capsule opacification (PCO) after cataract surgery, a serious complication that affects vision and requires additional treatment, is ~30%. In this study, we will investigate differences in PCO, presence of fibronectin, and ciliary ring distortion between lenses in eyes obtained from private and public eye banks. Overall, 500 eyes from patients with intraocular lenses will be analyzed. PCO, presence of fibronectin, and ciliary ring deformation will be assessed by experienced pathologists. We believe that our results will corroborate a pilot project in which eyes implanted with Acrysof and Acrysof Natural lenses (Alcon Laboratories) will experience less PCO relative to other lens types. Alcon will be able to market their products using these data. Moreover, healthcare providers will be encouraged to increase their use of the Acrysof products, thereby reducing the the overall burden of PCO.

View Full Project Description
Faculty Supervisor:

Miguel Burnier

Student:

Partner:

Alcon Canada Inc;Research Institute of the McGill University Health Centre

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Manufacturing

University:

Research Institute of the McGill University Health Centre

Program:

Elevate

Raman micro-spectroscopy for biopsy for prostate cancer prognosis -Year two

Prostate biopsies can be difficult to interpret using standard pathology techniques. Because cancer can be fatal, the development of technologies providing complementary information could improve current pathology practice resulting in improved patient outcome. Raman micro-spectroscopy is a molecular imaging technique using backscattered light following tissue laser excitation to indicate whether or not prostate samples contain cancer cells. However, this technique is very sensitive to the molecules in chemicals used to process tissue (e.g. paraffin), which greatly limits its efficacy. We will develop a standardized protocol for the preparation of diagnostic tissues insuring the rich molecular content of Raman imaging can be fully exploited for clinical use. Raman micro-spectroscopy is a label-free technique not requiring the use of dyes or molecular reporters, thereby greatly facilitating its use. The integration of this technique would improve our capacity to establish the prognosis of prostate cancer patients and advance research supported by ICM.

View Full Project Description
Faculty Supervisor:

Dominique Trudel

Student:

Partner:

Institut du cancer de Montréal

Discipline:

Life Sciences

Sector:

Other services (except public administration); Professional, scientific and technical services

University:

Université de Montréal

Program:

Elevate

Raman micro-spectroscopy for biopsy for prostate cancer prognosis

Prostate biopsies can be difficult to interpret using standard pathology techniques. Because cancer can be fatal, the development of technologies providing complementary information could improve current pathology practice resulting in improved patient outcome. Raman micro-spectroscopy is a molecular imaging technique using backscattered light following tissue laser excitation to indicate whether or not prostate samples contain cancer cells. However, this technique is very sensitive to the molecules in chemicals used to process tissue (e.g. paraffin), which greatly limits its efficacy. We will develop a standardized protocol for the preparation of diagnostic tissues insuring the rich molecular content of Raman imaging can be fully exploited for clinical use. Raman micro-spectroscopy is a label-free technique not requiring the use of dyes or molecular reporters, thereby greatly facilitating its use. The integration of this technique would improve our capacity to establish the prognosis of prostate cancer patients and advance research supported by ICM.

View Full Project Description
Faculty Supervisor:

Dominique Trudel

Student:

Partner:

Institut du cancer de Montréal

Discipline:

Life Sciences

Sector:

Other services (except public administration); Professional, scientific and technical services

University:

Université de Montréal

Program:

Elevate

Identification et aide à l’implantation d’un modèle d’écosystème entrepreneurial pour l’arrondissement Saint-Laurent de Montréal

Afin d’améliorer le sort économique de l’arrondissement Saint-Laurent, DESTL souhaite créer un lien de collaboration entre les grandes entreprises, les PME et les start-ups. Ceci est dans le but de générer de la valeur ajoutée tant pour les entreprises que pour l’arrondissement. Cette tâche n’est pas sans difficulté et nécessite un exercice rigoureux de recherche afin de garantir sa réussite. Le doctorant aura donc comme tâche principale de proposer le modèle qui s’applique le mieux au contexte de l’arrondissement Saint-Laurent.

View Full Project Description
Faculty Supervisor:

Jean-François Guertin

Student:

Partner:

Développement Économique Saint-Laurent

Discipline:

Business

Sector:

Administrative and support, waste management and remediation services

University:

Université de Sherbrooke

Program:

Accelerate

Development of nanobodies against Salmonella enterica and Campylobacter jejuni

The human pathogenic bacteria Salmonella enterica and Campylobacter jejuni are commonly found in the intestine of poultry. Consumption of infected chicken and eggs, and its derivatives, is the main and most important source of infection outbreaks in humans and causing diarrhoea, fevers and abdominal cramps. In some cases, severe diarrhea and dehydration followed by systemic spreading of these infections is life-threatening. At present no widely effective strategy is available to control both Salmonella and Campylobacter colonization of broiler chickens to prevent the infection in humans. To this end, AbCelex has developed a novel strategies of using nanobodies to control the level of Campylobacter and Salmonella in poultry meat by administering them as feed additives. Nanobodies are the smallest antibodies known in nature and are produced by members of the family Camelidae (like camels, llamas and alpacas) and sharks. This recently discovered antibodies present immunological and biotechnological advantages with respect to the conventional antibodies because they can be easily expressed in bacteria and produced in large quantities at a significantly lower cost. TO BE CONT’D

View Full Project Description
Faculty Supervisor:

Mauricio Terebiznik;Walid Houry;Emma Master

Student:

Partner:

AbCelex Technologies Inc

Discipline:

Life Sciences

Sector:

Agriculture; Professional, scientific and technical services

University:

University of Toronto Scarborough

Program:

Accelerate

Leacock Museum National Historic Site – Conservation Study

The research project will investigate and analyze a range of existing site and building conditions that may require upgrading and/or conservation at the existing Leacock Museum, former home of Canadian humourist, Stephen Leacock. The site is a National Historic Site, located in Orillia, Ontario. Research will be focused on: barrier free accessibility; exterior cladding; exterior historic woodwork condition; energy savings; and assessment of the site as a cultural heritage landscape. The research will provide +VG Architects, the sponsoring partner, site condition data and options for potential energy conservation strategies. This will assist +VG Architects in preparing a comprehensive planning document to assist in prioritizing future capital maintenance projects for this National Heritage Site.

View Full Project Description
Faculty Supervisor:

Robert Shipley

Student:

Partner:

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

University of Waterloo

Program:

Accelerate

Intégration des contraintes légales sur les horaires des chauffeurs de camion dans une solution de planification de la chaine logistique

“Afin d’assurer la sécurité des transports, de nombreuses réglementations existent autour du temps de travail pour les chauffeurs de camion. Elles définissent en particulier des durées maximums de conduite, et des périodes minimums de pause et de repos. Ces réglementations, souvent complexes, varient d’un état et d’un pays à l’autre. Pour que la chaine logistique soit efficace et donc que les livraisons se fassent à moindre coût, il est essentiel que les logiciels de planification des transports puissent tenir compte de ces contraintes afin de trouver les parcours de livraison les plus efficaces dans les limites de la réglementation.Le but de ce projet est double. Il s’agit d’une part de proposer une modélisation unifiée des principales réglementations existant à l’échelle mondiale, et d’autre part d’intégrer ces restrictions dans la suite logicielle de planification des transports de JDA Software.”

View Full Project Description
Faculty Supervisor:

Michel Gendreau

Student:

Partner:

JDA Software Canada Ltd

Discipline:

Mathematics

Sector:

Information and cultural industries; Professional, scientific and technical services

University:

École Polytechnique de Montréal

Program:

Elevate

Development of new generation of tool steels by modification in chemical composition, grain refinement, and cryogenic treatment – Year two

DK SPEC is a major producer of blades, cutters, and saws, made of tool steel, for the Canadian wood industry. In order to keep up with the stiff competition, the company has acquired some state-of-the-art heat treatment furnaces for cryogenic treatment. They have a complete cycle for machining, hardening, cryogenic and tempering cycles. They will shortly acquire a rolling machine in order to do deformation either cold or warm on the as-annealed materials before machining and final advanced heat treatment cycle. In this project new alloy will be designed and the developed knowledge and documentation during this project will help the industrial partner to implement the findings into its manufacturing process. The commitment, technical and operational contributions of company is clear indication of its interest to increase its technological level and produce high value added products.

View Full Project Description
Faculty Supervisor:

Mohammad Jahazi

Student:

Partner:

Dk Spec

Discipline:

Engineering

Sector:

Manufacturing

University:

École de technologie supérieure

Program:

Elevate

Development of new generation of tool steels by modification in chemical composition, grain refinement, and cryogenic treatment

DK SPEC is a major producer of cutting tool steels for the Canadian wood industry. A combination of High strength, good toughness, and wear resistance determines the quality of a tool steel. In the framework of Engage, EngagePlus and MITACS acceleration projects, an advanced heat treatment cycle by cryogenic cooling at temperatures as low as -100 °C was developed. The application of the above cycle resulted in a 75% reduction in processing time and improvement in wear resistance (+20%). However, in-depth thermodynamic and microstructural studies in the last three years showed that the chemical composition and microstructure of conventional tool steels do not meet the entire requirements for the cryogenic treatment. Therefore, the main objective of the project is to study new alloys compositions as well as new microstructure modification methods (e.g. cold or warm deformations) prior to the cryogenic treatment to achieve the superior mechanical properties required by industry.

View Full Project Description
Faculty Supervisor:

Mohammad Jahazi

Student:

Partner:

Dk Spec

Discipline:

Engineering

Sector:

Manufacturing

University:

École de technologie supérieure

Program:

Elevate

Approches génétiques à haut-débit appliquées au métabolisme microbien pour la prévention et le traitement des défauts de saveur du sirop d’érable

“Des métabolites présents dans la sève d’érable sont responsables d’un défaut de saveur de plus en plus préoccupant pour l’industrie acéricole, le défaut de « bourgeon ». Les objectifs du projet sont d’explorer les voies de traitement microbiologique possible dans la sève ainsi que dans le sirop d’érable:1. Étudier par des approches de séquençage à haut-débit, le métabolisme de divers microorganismes dans de la sève de qualité en contraste avec de la sève de « bourgeon » pour identifier les microorganismes ayant le meilleur potentiel pour métaboliser les précurseurs de défauts de saveur et ainsi neutraliser ces défauts avant leur apparition.2. À l’aide d’outils génétiques, utiliser le métabolisme de la levure comme rapporteur pour identifier des enzymes capables de dégrader les molécules responsables de divers types de défauts de saveur dans le sirop d’érable.”

View Full Project Description
Faculty Supervisor:

Christian Landry

Student:

Partner:

Centre ACER

Discipline:

Life Sciences

Sector:

Agriculture and Food; Biotechnology

University:

Université Laval

Program:

Elevate

Primary care nursing and prenatal education amongst pregnant woman in rural India

In India, maternal mortality rate is one of the highest in the world. It is therefore crucial to improve health care for pregnant women to prevent pregnancy complications, premature births and maternal and infant deaths. As the nurse is one of the key health professionals interacting with pregnant women, it is essential to redefine her role in health education and prevention of
infectious diseases. Infectious diseases such as hepatitis A and E are transmitted through the consumption of contaminated water. Therefore, the nurse and other health professionals should educate women to healthy water sterilization habits. Given this context, the outcomes of this project will be to define the role of the nurse in rural maternal health care, identify the major
barriers to access clean water for pregnant women in rural areas of Gujarat, and develop a health promotion intervention proposal for pregnant women of Gujarat raise awareness about the benefits of using clean water.

View Full Project Description
Faculty Supervisor:

Bilkis Vissandjée

Student:

Partner:

Indian Institute of Public Health Gandhinagar

Discipline:

Sociology

Sector:

University:

Université de Montréal

Program:

Globalink Research Award

Previous
1…324325326327328329330…2,595
Next

Join a thriving innovation ecosystem.

Subscribe to our newsletter now!

Subscribe

Mitacs — Return on Innovation

Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.