Enzyme-free, one-step nucleic-acid detection for point-of-care COVID-19 diagnostic screening

Rapid diagnostic testing has proven essential for stemming the on-going COVID-19 pandemic. Given the global threat of COVID-19 transmission, millions of tests are needed per month to isolate infections and to facilitate safe reopening of societies. This internship will contribute to COVID-19 diagnosis efforts by first developing a faster and cost-effective protocol for viral nucleic-acid […]

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Sparse array photodetector in multiplexed confocal FLIM

Confocal microscopy is a specialized imaging technique that is used by universities and pharmaceutical companies to perform drug discovery. The research team developed a multiplexing technique that can improve the imaging speed by 1000 times. In this project, the team will develop customized versions of the instrument with different cameras to cater to specific customer […]

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Modelling COVID-19 in humanized lungs ex vivo

The outbreak of COVID-19 has devastated the whole world. The conventional drug-discovery-pipeline to develop a new drug for this novel disease does not fulfill the immediate demand for a therapy. The scientific outcomes of in vitro models do not recapitulate the physiological conditions and in vivo models are not yet operational. Therefore, there is a […]

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Extraction, chemical analysis, and formulation development of potential anti-viral plant isolates against SARS-CoV-2

The COVID-19 pandemic has had broad global ramifications and preventative strategies and treatments for the virus are crucial. PBG BioPharma has developed two plant-based isolates, PBG-005 & PBG-007, that have shown innate immunological properties, potentially usable in the treatment or prevention of multi-viral infections. This research proposes leveraging PBG-005 & PGB-007, as well as PBG’s […]

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Robust Magnetic Resonance Imaging of Short T2 Tissues – Part 2

Magnetic resonance imaging (MRI) is an imagig modality which can visualize the internal structure of the human body and is free of radiation. In this project, we would like to write a multi-functional and robust MRI software package using ultrashort echo time (UTE) technique to realize the imaging of the tissues, such as tendons, ligaments […]

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Utilization of high pressure processing (HPP) to deactivate viruses and pathogens

Hospitals, diagnostic laboratories and medical research organizations have witnessed an upsurge in the generation of biohazardous medical waste during the COVID-19 pandemic. This waste is potentially detrimental to the environment and public health and needs to be adequately decontaminated and disposed. Incineration is the most routinely employed technique to treat biohazardous waste but the method […]

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AI enabled audio-visual annotation for endoscopic procedures

Video endoscopy is the main diagnostic and screening method for cancer screening in the gastrointestinal (GI) tract. Currently, the endoscopic video is not sufficiently documented, which makes reviewing of these videos difficult. The research team will partner with the company to develop an audio/video recording technology to combine physician voice annotation of the video during […]

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Electrophysiological studies of medical cannabinoids on 3D human cerebral organoids and neuroglial cultures

Epilepsy, characterized by recurrent seizures, affects 1% of the population. More than 30% of patients are drug-resistant, a significant burden to their lives. New innovative ways to treat the disorder are needed. Cannabidiol (CBD), a nonpsychoactive compound derived from the cannabis plant, has been shown to be a promising new treatment for epilepsy. In collaboration […]

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Integration of multiple modalities and radar modules for vitals monitoring

This project will seek to use novel radar technology in addition to computer vision to remotely detect vital signs (Heart Rate, Respiratory Rate, Movement and Temperature) of multiple patients. This will help lead to decreased morbidity of patients in areas such as waiting rooms, hospital or police seclusion rooms and other unique environments such as […]

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Simulation and modifications of an industrial scale dehydrator

CanDry is currently in R&D stage developing a dehydrator for drying organic and in-organic materials. A prototype is built for testing purposes which will help to design a good quality product. For modifying the design of prototype, we need to simulate the electromagnetic behaviour of the system and run multiple tests to compare the simulation […]

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Structural modeling for glycosaminoglycan/peptide complexes

Glycosaminoglycans (GAGs) are biological anchors for growth factors (GF) and other chemical substances. The binding of these substances to GAGs can be modified in times of need. For example during wound healing the increased number of GAGs in the injured areas enables a very localized increase in growth factors and chemokines necessary for wound healing. […]

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