Investigation of heavy metal bioavailability and bioaccesibility in SierraSil® mineral complex and its impacts on inflammation and bioavailability of other medications and natural health products

This study will provide the information about the in vitro bioavailability of As and Pb in SierraSil® at the first time and validate the possible product specific bioaccessibility method that can be used to predict bioavailability. This study will first compare the mineral composition of SierraSil® after acid and alkaline digestion, thus it is possible […]

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Characterizing microflora composition during the spontaneous fermentation of cassava flour

Quejos Ancient Foods (QAF) Inc. manufactures a line of dough-based food products that are gluten-free, grain-free, yeast-free, sugar-free. The dough is made from cassava flour, which has high concentration of carbohydrates and is rich in micronutrients. Traditionally, the cassava flour undergoes fermentation without the addition of yeast before the dough is made, and this process […]

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Developing Strategic Planning Tools to Support Forest Industry Transformation

Much of the management theory taught in today’s classrooms is focused on consumer-based, growth businesses rather than natural resource-based, cyclical industries. This study will examine how natural resource industries, such as forestry, recognize and adapt to structural (permanent) challenges in their market environment. The research will have three main components: first, using publically available information […]

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Social cartographies of initiatives of social transformation

Social transformation requires a deep understanding of the cultural, economic and historical forces and flows that connect peoples, places, and world views, and of the difficulties of intervening in complex, dynamic systems. This research project uses the methodology of social cartography to map diverse (and potentially conflicting) interests, ambitions and orientations of socially engaged communities […]

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Automation of Natural Fibre Properties Analyses

With increasing interest in the use of natural fibres, quality characterization is needed to provide benchmarks and uniform standards in order to use the abundance of natural fibre products in niche and higher value markets. Natural fibres are inexpensive, biodegradable and leave no waste, and are sustainable and readily available throughout Canada. By utilizing natural […]

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Efficient Implementation of IDA for Evaluating Seismic Response of Tall Buildings

One of the primary goals in tall building codes and standards is to protect life safety of inhabitants during earthquakes. Several methodologies have been proposed to achieve a proper performance of buildings. In this proposal, a recent method is applied using a series of nonlinear dynamic analyses under an appropriate suite of ground motion records. […]

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Enhancing exercise capacity and performance in elite Wheelchair Rugby athletes

This project aims to assess a number of novel exercise training techniques to improve exercise performance in elite Canadian Wheelchair Rugby athletes. The first training technique to be assessed is training in the heat, a condition that many Wheelchair Rugby players may have difficulty competing in, to lead to adaptations that will improve performance in […]

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Small scale high efficiency purification of compounds

We are developing a new generation of devices for continuous chemical and nano-particle purification, based on the interactions of analyte with multiple types of driving forces in an electro-fluid-dynamic system. The two-dimensional electrofluid-dynamic (2-D EFD) devices, in which both electric field and hydrodynamic pressure are simultaneously utilized in 2-D channel networks to drive the mass […]

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Targeting the GAS6/AXL Pathway in Acute Myeloid Leukemia Stem Cells with a Novel Combination Therapy

Blood cancer (leukemia) is common, with ~48,600 and 6,400 new cases expected in the United States and Canada respectively in 2016. The National Cancer Institute (US) calculated an overall 5-year survival rate of 56% for various blood cancers. This is because most current therapies are short-lived; drug resistance and relapse pose significant clinical problems. Life-long […]

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In-vivo translation of neuronal cell regeneration/reprogramming protein in mouse with chronic spinal cord injury

Chronic spinal cord injury (SCI) is a debilitating disease with enormous economic and personal impact. To date there is no approved treatment that can repair the severed nerves found in SCI. The research project entails translational development of an early stage experimental protein drug candidate that has shown remarkable ability to trigger dormant human stem […]

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