Drugs that inhibit a protein’s function do so by binding that protein and blocking interfaces relevant to its activity. This requires drugs to have high affinities towards and to be in high excess of their targets. Another approach called Proteolysis targeting chimeras (PROTACs) can be used, which hijacks a cell’s protein-degradation pathway by linking an […]

The decline in many populations of wild Pacific salmon is of great concern given their critical importance to First Nations, the ecosystems of the Pacific Northwest, and wild and farmed fisheries. The conservation efforts of the Pacific Salmon Foundation (PSF) have provided opportunity for research into infectious diseases like Heart and Skeletal Muscle Inflammation (HSMI) […]

Community stewardship is an emerging paradigm in income generation activities for marginalized populations. Drawing on residents with lived experience, stewardship creates employment through utilizing local-residents as custodians in parks, plazas and other public spaces. In order to fully develop these opportunities a common curriculum needs to be developed. This training program will allow Downtown Eastside […]

Digital imaging has become a leading feature in cell phones, security camera and satellite images. In addition to a race for picture clarity, the opportunities for data analysis and artificial intelligence (AI) are among the key elements attracting attention. The emergence of image enhancement and AI is relatively new, although it has a number of […]

The Canadian Association for Graduate Studies (CAGS) has created aTask Force on Truth and Reconciliation Calls to Action and Graduate Education (Reconciliation Task Force). This Reconciliation Task Force will examine the implications for graduate education in relation to the Truth and Reconciliation Commission of Canada’s (TRC) Calls to Action, to reflect on the role of […]

For the Inuit communities that reside in the Canadian Arctic, climate change and regional development have impacted people’s access to essential resources and their preservation of Inuit knowledge. By partnering with the Arctic Eider Society (AES) and Ocean Wise Ikaarvik program, I will translate my primary research in phytoplankton remote sensing into relevant information for […]

Next-generation sequencing (NGS) panels are gaining popularity thanks to the high-throughput capability of sequencing technology and low cost per sample. In this study, we aim to validate the performance of a NGS panel for detection of a rare genetic sterol disorder, and to assess the utility of a prediction model to identify a combination of […]

Cell migration assays (CMA) are fundamental cellular functional tests that are routinely performed in many areas of cell research such as tissue development, wound healing, cancer metastasis and immune response. We have developed a prototype microfluidic all-on-chip CMA that allows rapid immune cell migration assay tested directly from one drop of whole blood. This chip […]

Screening candidates for hourly-paid jobs based on resumes is time consuming and unreliable. deepND is seeking to understand which traits are shared by a company’s top employees – and how to assess for these traits using data sources at the earliest stages of the recruitment process. The definitions of employee success and performance are often […]

Centrate from food waste processing facilities contains higher concentrations of organic matters. Those contaminants (especially ammonia nitrogen) remain in the wastewater effluent after anaerobic digestion treatment, which are the great treat to the environment if not properly treated. Other contaminants (biochemical oxygen demand, chemical oxygen demand, total nitrogen, total phosphorus, suspended solids, etc.) also impact […]

This project encompasses various sub-projects aimed at developing enhanced approaches that will facilitate higher performing machines, geared towards enabling the concept of factories of the future (FOF). While this concept is established, research on new approaches that facilitate FOF are still early. The project conducts research on several sub-projects that include machine learning based robotic […]

Because of pollution and climate change, reducing the use of energy produced using fossil fuels is a priority in the next few years. To reach the goal actions need to be taken such as increasing energy production using renewable sources and reducing consumptions. To save energy people should be aware of the energy they are […]