Enhancement of the process validation via characterization and optimization of mixing operations in the Sanofi Pasteur cutting-edge manufacturing facility designed for the production of 5-component acellular Pertussis, Diphtheria, and Tetanus vaccines

Sanofi Pasteur has established a cutting-edge facility for the production of different types of vaccines in Toronto. This state-of-the-art facility is comprised of various complex mixing operations, which play significant role in the vaccine production. Currently, there is lack of sufficient information about the hydrodynamics of these mixing units for the process validation. In this […]

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Intelligent Piezoelectric Transduction System for In-situ Health Monitoring of Concrete Elements

Concrete elements are extensively used in urban structures including high-rises, bridges, dams and tunnels, and testing their quality and monitoring their health is of extremely high importance in the industry. In this project, use of piezoelectric transducers along with wireless communication and memory elements is suggested to overcome the limitations with the current methods. Piezoelectric […]

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Medicinal Chemistry Studies on Small Molecule Glucocerebrosidase Inhibitors

The objective of this internship is to create new chemical compounds that can be used to further our research and understanding of a human enzyme known as GBA2 – implicated in several debilitating diseases and signalling pathways in the body. These compounds would not only serve as tools to probe GBA2 for additional information but […]

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Integrating state-of-the-art sustainable design with heritage conservation through an online information system

Although ambitious climate change laws are encouraging the sustainable retrofits required to meet carbon emissions reductions targets, a lack of understanding of the synergies between sustainability and preservation often results in interventions which adversely impact heritage values or are less effective than they could have been. Interns will work with MTBA Associates, Inc. to gather, […]

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Investigating the effect of the Virtual Meditative Walk on brain in chronic pain conditions: A longitudinal fMRI study

The Virtual Meditative Walk (VMW) (1) is a well-developed therapeutic protocol that can be used alone or in combination with the Mindfulness-Based Stress Reduction techniques in an Immersive Virtual Reality (IVR) environment. It has been shown to be effective in reducing pain levels in patients with chronic pain (CP); however, little is known about how […]

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Development of polymer bonded / sintered permanent magnets for a wearable NMR sensor

SYNEX Medical, a Toronto based biotechnology startup has developed a non-invasive biomarker technology that comes in the form of a wearable ring enabling users to track concentration of different biomarkers in their blood. The device employs Nuclear Magnetic Resonance (NMR) technology to determine the concentration of different biomarkers. One fundamental instrumentation for this NMR based […]

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Artificial Intelligence-based COVID-19 Radiology Image Analytics and Beyond

The excessive daily requirement for COVID-19 tests has put the healthcare providers in an overwhelming circumstance, especially in rural communities, with a limited number of resources. Moreover, the existing COVID-19 screening technique is time-consuming and expensive, which can be a luxury for many communities. Thus, in this research project, in collaboration with the TBRHRI, we […]

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The Power of Peer Support: The Development and Evaluation of JAVAGROUPS-digital

Social isolation and loneliness have become a global public health concern affecting the majority of seniors living in care settings and seniors living in the community. Due to COVID-19 and physical distancing these numbers are dramatically increasing. Java Group Programs have developed three evidence-based peer support and mentoring programs that offer emotional support through structured […]

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Evaluation, optimization and modeling of sequencing batch reactors (SBR) operation for treatment of municipal wastewater

Sequencing batch reactor (SBR) is an activated sludge process that has been used successfully in municipal and industrial wastewater treatment. SBR process is operated in a batch mode where different batch phases run successively in a single tank or several tanks operating in parallel. Many studies on real-time control strategies have been employed to check […]

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Development of a New Family of Agri-based Flocculent for Optimized Water & Nutrient Recovery from Anaerobic Digestate

Anaerobic Digesters are used in farm-based, municipal and industrial settings to convert wastes (manure and crop residues) as well as other feedstock material (fat, grease, oil and food wastes) to biogas. Produced digestate is rich in nutrients such as phosphate, nitrogen, (and other minor nutrients) and is mixed with water that makes the transportation costly […]

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The Impact of Sustained Time in Human Care on the Migratory Behaviour of the Endangered Loggerhead Shrike

Our research will assess the degree to which variation in migratory behavior in Loggerhead Shrike is altered due to sustained periods of captivity. Information will be obtained from a captive population of Loggerhead Shrike. Behaviour of captive birds will be recorded on video cameras and analyzed to determine the level of migratoriness displayed by differently […]

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Development of the early immune response assay in saliva

The current coronavirus outbreak highlights the importance of point-of-care (POC) rapid screening tools to identify and understand COVID-19 spread within the population. As countries work on flattening the disease curve, it is anticipated that billions of COVID-19 tests will be required for the next 12-24 months. Also, it is widely understood that the next pandemic […]

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