Next Generation Selective Nanocomposite Fibrous Membrane for Energy Recovery Ventilators – Year two

Heating and cooling in residential and commercial buildings account for 20% of total energy consumption in Canada. Conditioning indoor air using less energy is closely associated with minimizing production of greenhouse gases and making a sustainable global environment. In this study, we apply a nanocomposite fibrous membrane for an energy recovery ventilator (ERV). Heat and […]

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Experimental and Mathematical Modeling of Flow Instability in Heavy Oil Recovery Processes – Year two

This research project with the industry partner Saskatchewan Research Council focuses on the displacement front instability in heavy oil recovery processes such as water flooding, solvent injection and polymer flooding. In those processes, the less viscous displacing fluid usually moves faster than the more viscous displaced heavy oil. This results in an instability that manifests […]

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Formulation and Toxicology of Bone-Targeting Nanoparticles – Year two

Bones undergo a renewal process by replenishing calcium mineral through a cellular process known as remodeling. Usually, it happens in a balanced manner, but in many bone diseases, the remodeling process is increased with regional bone metabolism. Bisphosphonate (BP) drugs selectivity and strongly bind to bone mineral and become incorporated at active sites of bone […]

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Effects of dietary glutathione precursors on cellular redox and mitochondrial efficiency in adults consuming a defined hypocaloric diet (Optifast-900; Nestlé Canada)

The aim of the proposed research is to investigate the cellular mechanistic effects of supplementation with a hypocaloric meal replacement product (Optifast-900; Nestlé Canada) containing cysteine and glycine, which are amino acid precursors of the antioxidant glutathione. Impaired cellular glutathione redox normally occurs with aging and metabolic disorders, however, this study will focus on a […]

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Validation and Development of Clinically Relevant Copper Complexes for the Treatment of Bacterial Infections

Nearly 70% of all drug candidates are not pursued for pharmaceutical development because they cannot be dissolved into solutions appropriate for human use. Cuprous Pharmaceuticals Inc. (CPI) recently discovered that some of these drugs could be dissolved in the presence of certain metal ions. Furthermore, a number of metal-drug complexes are more therapeutically active than […]

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Electrochemical Impedance Modeling and Optimization of Li-Ion Battery Utility using Active Battery Management System (ActiveBMS)

Lithium ion batteries (LIBs) are considered the top candidates among electrochemical energy storage systems (ESS) due to their high energy density which has triggered the growth market of popular devices such as cell phones, computers, electric vehicles (EV) etc. As ESS, LIBs are continuously charged and discharged during their utility. The charge/discharge cycle is known […]

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Achieving aspirations of Canadian aboriginal communities through participatory cultural mapping and dynamic decision modelling

The aspirations of aboriginal communities are a critical part of decision making regarding land and resource use, policy and community development, and strategic planning. To help achieve aboriginal aspirations, this project aims to develop, apply, and evaluate a novel approach to aid aboriginal community decision making and solution creation/implementation. This approach builds upon current research […]

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Feasibility Evaluation Study of LifeguardMobile (designed for supported self-management of patients with chronic and complex conditions) – Year two

“Lifeguard Health Networks Inc. (LHN) has developed a secure Virtual Health Assistant application (app), to enhance supported self-management for patients with chronic and complex conditions, by leveraging their network of trusted family and friends, under the direction and guidance of health practitioners.We are conducting a study to evaluate the feasibility of the app and the […]

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Autonomous Sensor System for Monitoring Torque from the Flexplate – Year two

While torque is an important parameter in automotive performance, there are currently very few effective methods to monitor it in vehicles. The aim of this project is to develop a low-cost solution for real time engine torque monitoring. An autonomous sensor module will be developed and mounted to the flexplate connecting the engine and the […]

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Optical determination of membrane defects and correlation with fuel cell performance and durability – Year two

There is a strong push toward producing fuel cells on a commercial scale. This means a greater focus on production speed and yields with a need to understand the unintended features that arise from larger-scale manufacturing processes. This project requires the set up of state-of-the-art, camera-vision, defect detection equipment to find and collect observed membrane […]

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Development of Ex-situ Mechanical Durability Tools and Thermo-mechanical Design Curves for Fuel Cell Membranes – Year two

Hydrogen powered polymer electrolyte membrane fuel cells (PEMFCs) are a clean energy technology that generates electricity without harmful emissions at the point of use. Current R&D efforts mainly target to commercialize PEMFCs through cost reduction and durability enhancement. The lifetime of PEMFC is limited by the degradation and failure of the polymer electrolyte membrane (PEM). […]

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Multi-biomarker test for the management of acute cardiac transplant rejection

The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately and efficiently diagnosing when organ rejection occurs. In Canada, the current approach to diagnosing acute rejection requires taking small pieces of the […]

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