In this research project, the separator of rechargeable hybrid aqueous batteries (REHABs) is mechanically strengthened with graphene oxide derivatives. ReHABs comprise of a lithium intercalation cathode, zinc anode and an aqueous electrolyte. One of the problems with current ReHABs is the zinc dendritic growth and propagation from the anode, which significantly reduces its operating lifetime. […]

Gene therapy is one of the most attractive new therapeutic strategies in the treatment of multiple diseases. However, to apply gene therapy in clinic, an efficient and safe delivery system must be developed to transport these therapeutic reagents to target organs. The existing gene carriers suffer from either high cytotoxicity or immunogenicity problems, which will […]

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

The project deals with the production of non-structural composite interior coverings for aircraft and other vehicles. Producing such interior coverings in Canada requires very good mastery of manufacturing processes in order to contain costs. Target times for preform preparation are of the order of minutes and manufacturing processes remain largely manual. Competition from emerging countries […]

The purpose of this study is to gather information relating to the one-way degassing valves used within the coffee industry in order to improve upon current designs. This will be achieved through studying the opening/closing properties of commercial valves, as well as using a model system to elucidate the effects of valve components on these […]

Our goal is to continue to provide the solution to the problems that elementary schools are facing across Ontario. To re-define the existing culture of recess by providing healthy role models, options and equipment and advocating for spaces more conducive to play. Our research team is currently the only one in Canada dedicated to research […]

The goal of this project is to provide evidence of validity for two newly developed measures of quality of life; one for hidradenitis suppurativa (HS) and one for acne. Both HS and acne negatively impact quality of life; however, to date, there are no disease-specific, patient-centered quality of life measures. The results of this project […]

Traditional research microscopy tools are entirely adequate for conventional static analysis, however, the evaluation of more complex dynamic cellular processes require unconventional methods of acquiring, displaying, and rendering dynamic data. Autophagy occurs when some of a cell’s cytoplasm, referred as cargo, is enclosed by a membrane to form an autophagosome in order to be degraded […]

The promotion and maintenance of men’s pelvic floor health is a growing concern as pelvic disorders affect a substantial number of men and their prevalence is expected to increase as a result of Canada’s aging population. Pelvic floor disorders go beyond their physical consequences as they can negatively impact men’s psychological, sexual, and social quality […]

With a rise in talent and the number of youths participating in athletics, Canada has a seemingly bright future in track and field at the international level. With the abundance of talent, it is important to improve the resources available to our competitors to continue promoting excellence. We propose to study two novel protocols which […]

Low back pain is a leading cause of disability worldwide. The Canadian Armed Forces (CF) has a greater incidence of LBP than the general population. LBP is responsible for a large proportion of medical releases in the CF with many cases resulting in lifelong pain and disability. Improved early access to evidence-based care could help […]

The intern will use the company’s proprietary biomaterials to create tumors using cancer cells. These tumors can be used as an alternative to animal testing for cancer drugs. These cancer models will cost a fraction of the cost of animal models and can be tested using existing pharmaceutical techniques and equipment. The intern will develop […]