The intern will be producing a therapeutic protein, i.e. ‘biologic’ (BMP2) using mutated bacterial plasmids as the bio-factory. The intern will create a sequence of DNA to be transformed into E. coli cells (BL21). The cells will be grown up in the lab, and studied for enhanced clinical efficacy. Proteins will be affinity purified and […]

This project is a systemic review and assessment of diversity strategies currently in place at The Scarborough Hospital using the Diversity Institute’s Diversity Audit Tool (DAT). The DAT was developed based on research into leading practices and offers a lens through which diversity strategies can be analyzed; this will be the first time that it […]

Dizziness is among the top three reasons that patients seek medical attention, and one of the most common disabling conditions that humans face. One of the diseases that may cause dizziness is Meniere’s disease, which its correct and timely diagnosis and separation from other causes of dizziness with current techniques are quite challenging. On the […]

In this research we propose to carry out a feasibility study to identify an ultrasound transducer that can be used specifically for breast cancer tumor detection. This transducer will be interfaced with the available Ultrasonix Elastrography System at SFU. This will be the most significant part of the proposed research. It will include assimilation of […]

This project will provide a snapshot of diversity in hospitals in the Greater Toronto Area (GTA). There are a number of culturally diverse groups (e.g., visible minorities, women) who face barriers to accessing healthcare services in Ontario as well as preventing their full workforce participation. In order to identify and address these barriers, diversity strategies […]

Major depressive disorder (MDD) is a serious mental condition that often completely debilitates a client. MDD is typically treated with one of several currently available antidepressant medications. However, the response rate to any of these medications is only about 30%. Unfortunately, there are currently no means for a priori assessment of whether a specific person […]

The aim of this grant proposal is to address the challenges with current CT Coronary Angiography (CTCA) utilization with a comprehensive series of interrelated but well-defined research themes. This non-invasive technique has facilitated in the detection of significant coronary artery disease and vulnerable plaque. However, the quality is limited to the physicality of the patients […]

The loss of bone is a massive burden on the health care system and severely impacts the quality of life of several hundred million people. The need for alternative strategies to replace or regenerate bone tissue is overwhelming. We are proposing a completely new approach to the engineering of bone using a ―cocktail‖ of genetically […]

The diagnosis of HIV & AIDS complicates sexual activity. Physiological and psycho-social factors such as body image, fear of rejection, and stigma can lead to shame and isolation. The purpose of the present study is to gain a greater understanding of the range of barriers to sexual intimacy that persons living with HIV and AIDS […]

  Water quality is critical for a many human activities. With respect to recreational water, a particular type of water source, there are often relatively high levels of microbial contamination in relation to other types of water sources (e.g., drinking water). E. coli is used as a microbial indicator for water quality because E. coli […]

Antipsychotic medication is associated with a constellation of metabolic abnormalities, including weight gain, an imbalance between glucose and insulin actions, and higher than normal lipid content. In particular, adolescent psychiatric patients are at increased risk for Type II Diabetes and cardiovascular disease when undergoing therapeutic treatment. Current analysis indicates that antipsychotic drugs have differing effects […]

  One of the major obstacles that hinders the adaption of the digital pathology solutions is the inadequate performance and network overload for pathology image storage and retrieval. A common technical problem is the limited bandwidth of the network and the delayed  transmission speed of digital images to the viewing station. There is an urgent […]