Informing the Conservation and Management of Pacific Herring on Canada’s West Coast

The complexity of movement and behaviour in Pacific herring (Clupea pallasii) stocks targeted by commercial and indigenous fisheries in BC is poorly understood and often discounted in fisheries management policies, possibly contributing to recent stock declines. We propose to inform spatial management strategies for herring on the central coast of BC with (I) local knowledge […]

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Targeting CD36 cell surface receptor to treat macrophage-induced chronic inflammation

Chronic inflammation is the common denominator for various diseases, including atherosclerosis, age-related macular degeneration (AMD), obesity, type-2 diabetes, liver diseases and even cancers. In most cases, this inflammation is the result of massive pro-inflammatory macrophage infiltration in tissues, due to their aberrant signalling and dysfunction, in presence of fat accumulation. The CD36 scavenger receptor has […]

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Physiological Assessment and Analysis of the Physical Demand of Riding a Snowmobile

The purpose of the present study is to evaluate scientifically the physical demand associated with the safe operation of a snowmobile under typical (normal) riding conditions experienced by North American snowmobilers. We will quantify the physical demand of snowmobile riding and compare this to national recommendations for the promotion of health and fitness, as well […]

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Application, efficacy and scale up of a novel extraction method for valorization of by-products of Ascophyllum nodosum extract processing

The industry partner is a producer of a successful seaweed based plant product used globally to improve plant growth. However, a large amount of waste byproduct, termed seaweed insoluble residue, is created as a byproduct of the production process. This residue has been found to contain a large amount of the original seaweed biomass. By […]

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Heap leaching of refractory gold ore by integrating enhanced bio-oxidation of pyrite and chloride-based gold leaching

Gold occurs in association with pyrite and arsenopyrite in the Carlin-type gold deposit, with little gold being contained in carbonaceous materials. Extracting this gold requires pretreatment, such as pressure oxidation or roasting, to remove carbonaceous materials and sulphides, followed by the application of alkali cyanide or thiosulphate solution to leach gold. These processes are energy-intensive […]

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Investigations in real-time spinal magnetometry using magnetoencephalography (MEG) for therapeutic biofeedback

Oscillatory neuronal activity can be quantified to help diagnose states of health and disease in the brain. These activities change on a fast time scale of milliseconds, which can only be captured by direct measurement of the brain’s electromagnetic activity. This is accomplished utilizing MEG and EEG technology, which can measure non-invasively these fast changes […]

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Web-based mobile mental health technology in an acute care setting

The use of mobile technology is on the rise including access to mental health-related applications and websites. There is a wealth of information available and numerous intervention strategies focused on treatment and support for mental health concerns. However, inpatient psychiatry often discourages patients’ use of electronic technologies and web-accessible mobile phones. The proposed study involves […]

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Modern tools for selecting disease-resistance traits in honey bees

Over the past six and a half years we have developed a way to measure disease resistance in honey bees using a molecular diagnostic approach, similar to the tests done every day in hospital laboratories. We have then used this method to selectively breed bees that are, indeed, more resistant to disease. This is akin […]

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Deciphering the role of the tumor suppressor p53 in regulating treatment-induced ovarian cancer cell fate decisions in vivo

As the most lethal gynaecological cancer, ovarian cancers not only threaten lives of many women worldwide, but health side effects also burdens the life of millions patients following treatments. Novel therapeutic methods aiming at increasing the long-term survival of patients and decreasing health side effects associated with treatment is critical. We have already found that […]

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Molecular characterization, autogenous vaccine manufacturing and vaccine potency studies of two pathogenic Avian Reovirus (ARV) field isolates from the Province of Alberta

Avian Reovirus (ARV) is an economically important virus that is affecting poultry flocks in Alberta. Birds infected with pathogenic ARV may develop a disease named viral arthritis/tenosynovitis which is characterised by lameness, swollen joints, rupture of tendons and increase mortality. The disease is controlled by parent stock vaccination with live and/or inactivated antigen to provide […]

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Optimization of novel drugs to treat cardiac arrhythmias

This project aims to validate and optimize drugs to treat heart rhythm disorders. The heart is a complex organ that uses tiny electrical signals to maintain a healthy rhythm. When these electrical signals are disturbed, it can change the regular rhythm, which can result in life-threatening consequences such as sudden cardiac death. Here, I will […]

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