Development and validation of blood-based biomarkers for improved heart failure management

Chronic heart failure (HF) is an epidemic affecting approximately 1.5-2% of Canada’s population (12% in patients over 80yrs) and the current one-year mortality rate after HF diagnosis remains disturbingly high at 25-40%. Even with treatment, many HF patients require hospitalizations during the course of their disease; in Canada HF is responsible for $3 billion in hospital […]

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High-fidelity robotic simulation framework for artificially intelligent medical robot

There is a great need and benefit to integrate artificial intelligence, robotic simulation, and robotics technology into Canada’s medical industry, hospital environment, and healthcare system. Robotic simulation technology, which has been successfully used for space rover missions such as NASA’s Curiosity rover and the Mars Pathfinder and Sojourner mission, provides the ability to create and […]

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Low-shear, scalable microfluidic sorting of platelets and leukocytes for pooled platelet lysate

Extem supplies research grade mesenchymal stem cells (MSCs) and is looking to differentiate themselves by providing a proprietary human-derived growth media to replace the cow-derived fetal bovine serum (FBS) typically used. Pooled platelet lysate (PPL) may be a viable alternative. However, existing PPL methods lack quality control, standardization, and can result in up to 50% […]

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Tick vectored disease biobank

Lyme disease is one of the many diseases transmitted by ticks. The rate of these diseases is rapidly increasing in Canada. Diagnosing these diseases is difficult but examination of biopsy, necropsy and autopsy tissue can help to understand the full and varied effects of the disease and ultimately reduce misdiagnoses. Biobanks are required for this […]

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Processing of Linac Produced 99Mo, and Extraction and Validation of 99mTc using a unique 99Mo/99mTc generator system

Technetium-99m (99mTc) is a radioactive substance that is used in nuclear medicine departments worldwide. This substance when made in an appropriate formulation is injected in patients and following its decay pictures of the patient can be obtained. This pictures help physicians diagnose certain diseases notably cancers and heart diseases. The government of Canada historically was […]

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Predicting real-world attention with physiology

It is estimated that the average person spends up to 50% of their waking hours thinking about things other than what they are presently doing (i.e., mind wandering). This internal form of distraction along with its external counterpart (i.e., external distraction) are associated with performance deficits during everyday activities, such as reading or driving. Moreover, […]

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A One-Health approach to echinococcosis (Echinococcus multilocularis) in client owned dogs in Alberta: force of infection, risk factors, diagnostics, treatments and information

This project aims to determine prevalence rates of Echinococcus species tapeworms in domestic dogs and to compare these rates to those obtained from wild canids including wolves, coyotes, and foxes. This will shed light on infection rates and risk factors for both the human population and their pet dogs. This research will benefit Bayer as […]

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Validation of novel balance assessment software using Microsoft Kinect v2.0

Objective and reliable assessment of balance and postural sway has the ability to drastically improve the screening process for risk of falls among elderly populations. Standard assessment protocols and questionnaires are in place, however these do not provide objective, reliable fall prediction. Standard concussion assessment protocols determine the presence and severity of a concussion, as well […]

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Journeys to Engagement: Ambient Activity Technologies for Managing Behaviours in Dementia

The objective of this project is to work with an industrial partner (Eclectic Industries Inc.) to design an activity tracker for institutionalized individuals with dementia. In our previous work with Eclectic Industries Inc., we refined and evaluated Ambient Activity Technology (AAT). AAT is a wall-mounted interactive tool (accessible anytime) designed for people with dementia to […]

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