There is an unmet need to replace surgical plates and screws in small joint and non-loadbearing orthopaedic surgeries. Despite a clear clinical need and market opportunity, there are no products available today that address issues such as long surgery times, high cost, patient discomfort, and reoperation for metal implant removal. Dartmouth Medical Research, Ltd. is […]

The high prevalence of obstructive sleep apnea (OSA) poses a serious threat to the healthy growth and development of many children. The lack of oxygen during sleep can lead to daytime sleepiness, growth failure, behavioural problems and developmental delay. Polysomnography (PSG), the gold standard to diagnose OSA is high in cost, requires a well-equipped sleep […]

It is estimated that 1 in 2/3 people will be diagnosed with cancer in their lifetime. Cancer is a genetic disease characterized by the uncontrolled growth of cells. While treatments are available for many cancers, remission of the disease, side-effects of the medication, and the onset of resistance by the cancer to the drugs being […]

For people with lower limb amputations, the interface between the amputated limb and a prosthetic socket is very important. Suspension, or how the socket is held on the limb, is one factor that affects a person’s ability to walk efficiently and safely, movement confidence, limb health, and quality of life. This project will assess, evaluate, […]

Selective laser meting (SLM) is a promising additive manufacturing process that can be effectively utilized to manufacture structural components with complex geometries. Instead of removing the material, SLM adds the material selectively layer after layer using high power laser beam to form near net shape parts. Due to high cost associated with experimental development of […]

Streptococcus agalactiae (S. agalactiae) is a worldwide-distributed bacterium. It is a major infectious agent to humans, cattle and aquatic animals. The outbreak and prevalence of S. agalactiae in aquaculture has been reported in different countries as one of the major causes of mortality leading to serious economic losses and threatening the sound development of aquaculture. […]

We have previously developed and commercialized a bacteria detection technology that is now being marketed for testing E. coli and coliform bacteria in water. The work proposed here will provide tests for additional bacteria types, and new applications of current tests. Each new test will be a combination of new sample handling methods and additional […]

The purpose of the funding is to provide initial support towards the establishment of an Inter-disciplinary Assessment and Rehabilitation Centre for Excellence. This center will be initiated between the University of Toronto Scarborough (UTSC), Multi-Health Systems (MHS), Rehabilitation Research, Education and Evaluation Services (RREES), with consultation and data collection support by RTW Integrated Health Management […]

Microneedles are hollow needle structures made out of metal, polymer, or silicon which can be manufactured at any height up to one millimetre, with arrays from one to hundred microneedles, depending on the required playload for delivery. Microneedles platform technology can be applied in medical, cosmetic, biotechnology, and industrial applications. The partner organization has developed […]

Rates of obesity are continuously rising despite efforts to decrease them. The purpose of this study is to show that obese but fit individuals are protected from many adverse health conditions such as metabolic syndrome, insulin resistance, type-2 diabetes, high blood pressure, and cardiovascular disease as the result of being physically active. This study is […]

Qu Biologics is a clinical-stage biopharmaceutical company developing and evaluating an innovative immunotherapeutic approach to treating disease rooted in immune pathology/dysfunction. Qu’s proprietary technology platform, site-specific immunomodulators (SSI), act to stimulate the body’s own immune system to reverse the chronic inflammation underlying many conditions including cancer and immune-mediated diseases. For lung diseases, Qu’s platform SSI, […]

Current performance optimization models of track cycling are inadequate to estimate conditions such as the start of the race and during positional changes of the athletes. Monitoring muscle excitation is a valuable way to quantify metabolic changes since it does not discriminate the energy source. Muscle excitation is therefore a good parameter to explore the […]