Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

13270 Completed Projects

1072
AB
2795
BC
430
MB
106
NF
348
SK
4184
ON
2671
QC
43
PE
209
NB
474
NS

Projects by Category

10%
Computer science
9%
Engineering
1%
Engineering - biomedical
4%
Engineering - chemical / biological

Targeting CD36 cell surface receptor to treat macrophage-induced chronic inflammation

Chronic inflammation is the common denominator for various diseases, including atherosclerosis, age-related macular degeneration (AMD), obesity, type-2 diabetes, liver diseases and even cancers. In most cases, this inflammation is the result of massive pro-inflammatory macrophage infiltration in tissues, due to their aberrant signalling and dysfunction, in presence of fat accumulation. The CD36 scavenger receptor has been shown to be key player in inflammation, with its TLR2 co-receptor. Combined fat accumulation and formation of oxidized low-density lipoprotein (oxLDL) activate TLR2 receptor through the binding of oxLDL to CD36, and triggers the disproportional recruitment of pro-inflammatory macrophages causing the inflammation. The project aims to better understand the role of azapeptides with high CD36 affinity binding in the treatment of inflammation conditions.

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Faculty Supervisor:

Sylvain Chemtob

Student:

Ragnhild Ohm

Partner:

Mperia Therapeutics Inc

Discipline:

Medicine

Sector:

Life sciences

University:

Program:

Accelerate

The use of improved antibody drug conjugates for targeted treatment of bladder cancer – Year two

Bladder cancer is the fifth most common form of cancer in Canada, however progress in the development of safer and more effective therapies has been slow. The use of antibody drug conjugates (ADC) is a promising therapeutic option that would allow for targeted killing of cancer cells, if the obstacle of getting the drug inside the cell can be overcome. The proposed research project aims to use iProgen’s Antibody Internalization Domain technology to engineer ADCs targeted to bladder cancer, which can be readily taken into the cell. These improved ADCs will be tested in a number of pre-clinical cancer models, including a cutting-edge model in which human tumours are implanted into mice, creating avatars of the patient’s cancer.

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Faculty Supervisor:

Peter Black

Student:

Morgan Roberts

Partner:

iProgen

Discipline:

Medicine

Sector:

Pharmaceuticals

University:

University of British Columbia

Program:

Elevate

Improving decision-making by reducing anxiety

Performance anxiety has been shown to negatively impact decision-making as well as academic performance, but it is unclear whether the effect of anxiety on test performance is due to impaired decision-making. Audio-Visual Entrainment (AVE), which involves exposure to rhythmically pulsating light and sound, has been shown to relieve anxiety symptoms — thus, AVE may be able to improve decision-making by alleviating anxiety, which may translate to better academic test scores. We predict that participants who undergo AVE treatment will perform better on a multiple-choice intelligence test than participants who undergo a sham treatment or no treatment. This research will advance scientific understanding by helping to clarify the relationship between performance anxiety and test performance. It will also benefit the industry by highlighting the wide applicability of AVE technology, including in academic and professional settings.

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Faculty Supervisor:

Amir Raz

Student:

Derek Albert

Partner:

Mind Alive Inc

Discipline:

Psychology

Sector:

Medical devices

University:

McGill University

Program:

Accelerate

Advancing Unstructured Data Extraction and its Use in Geoscience

Unstructured data refers to data that is present in reports, web pages, newspapers and other media. Such data is the most common data that we see around us and yet no modern tools exist to extract information from it. In this project we will develop techniques to extract the data and apply it to geoscientific reports in order to aid in the discovery of new mines and other geoscience applications.

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Faculty Supervisor:

Eldad Haber

Student:

Alireza Shafaei

Partner:

Xtract Technologies Inc

Discipline:

Computer science

Sector:

Mining and quarrying

University:

University of British Columbia

Program:

Accelerate

Improving implementation of the intensive lifestyle intervention and accuracy of lifestyle data collection in the REMIT-Dapa trial.

Type 2 diabetes (T2D) results in high blood sugars and can cause serious complications. Recent studies suggest that treatment with diabetes medications along with lifestyle changes can result in patients not needing diabetes medications for months or even years, a concept known as diabetes remission. The Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT) pilot trial was done to look at the effect of lifestyle changes and diabetes medications in people with T2D. A large REMIT trial was recently started to look at the effect of a similar intervention in causing diabetes remission. The lifestyle changes involve >5% weight loss and 150 minutes of physical activity per week. It would be worthwhile to assess techniques used by the research nurse, dietitian and kinesiologist that contributed to people accomplishing their lifestyle goals. It is also worthwhile to look at people who accomplished their lifestyle goals and see what helped them be successful. The aim of this analysis is to provide this information to centres facing difficulties achieving the lifestyle component. Also, there is an opportunity to improve the way physical activity and diet information is collected during the current trial.

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Faculty Supervisor:

Natalia McInnes

Student:

Farah Sultan

Partner:

AstraZeneca

Discipline:

Medicine

Sector:

Medical devices

University:

McMaster University

Program:

Accelerate

Optimization of Euglena Fatty Acid Production: an Important Step towards the Commercialization of Euglena Oil

Noblegen Inc. is an advanced bioproducts manufacturer dedicated to developing cost-effective, naturally-derived biomaterials and biochemicals for a wide range of consumer and industry sectors. We employ a unique organism, algae, to continue to do what it does naturally – decontaminate wastewater sustainably and affordably while also generating valuable biomass for use in biomaterials and biochemicals production. In this research, we propose to investigate the effect of various culture conditions and strategies in order to optimize the culture protocol for increasing oil production with a desired FA composition derived from algal biomass.

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Faculty Supervisor:

RJ Neil Emery

Student:

Thien Nguyen

Partner:

Noblegen

Discipline:

Biology

Sector:

Environmental industry

University:

Trent University

Program:

Accelerate

Ciena OPn – WP 3.1.1 Supply Chain Agility, Life Cycle Management and Forecast Accuracy

Ciena Corporation is a global supplier of telecommunications networking equipment. It develops this equipment in a high product mix, low volume environment. Due to this environment and the short cycle times of its products, the company has product categories, which are highly dynamic both in volume and number of customers. Ciena wishes to be more agile in managing its supply chain. It also wishes to better predict the dynamics of product volume and product end-of-life over short timeframes. Consequently, the objectives of the project are to improve the accuracy of production volume estimation during product life cycles, to develop methods that more quickly signal supply chain partners about changes in demand, and to create a computer-based tool that captures supply chain information and assists managers to adjust Ciena’s supply chain activities on a daily basis.

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Faculty Supervisor:

Vince Thomson

Student:

Xiaoqi Zhang

Partner:

Ciena Corp.

Discipline:

Engineering - mechanical

Sector:

Information and communications technologies

University:

McGill University

Program:

Accelerate

Advance Silicon-based lithium-ion batteries

In this project, an advanced silicon-based lithium ion battery will be manufactured. The expected energy density is 750-1000Wh/L and cycle life is about 2000 time (capacity remaining rate>80%), which means the working time of your cell phone, laptop can be extended to 3-5 times on a charge and they can maintain a good working condition even it has been used over 5-8 years. The best news is that you don’t need to pay extra. Through this study, the manufacture technology of the silicon-based electrode will be developed from laboratory level to application. After some optimization study of positive electrode and electrolyte selection, a mobile-phone-capacity pouch cell (about 2000mAh-3000mAh) will be fabricated.

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Faculty Supervisor:

Michael Fowler

Student:

Zhiyu Mao

Partner:

Newtech Power

Discipline:

Engineering - chemical / biological

Sector:

Advanced manufacturing

University:

University of Waterloo

Program:

Accelerate

Leveraging genomic information to better understand the biological effect of major genes on reproduction and health traits in dairy cattle

The main objective of the study is to increase the discovery of important reproduction and health genetic variants in dairy cattle. This could help improve reproduction and health of dairy herds through genomic selection or editing of the genome. In order to find the causative variants affecting reproduction and health traits, a review of the literature will be performed and new and cutting-edge genomic technology will be used. The transmission ratio distortion concept will allow the discovery of new regions affecting reproduction, while genome-wide association studies and functional analysis will allow the validation of these regions. Using these results, the partner organization could possibly produce genetic material that would allow dairy producers across Canada to be more efficient and to improve the reproduction and health of their dairy herds.

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Faculty Supervisor:

Angela Canovas

Student:

Cindy Jaton

Partner:

Semex Alliance

Discipline:

Animal science

Sector:

Agriculture

University:

University of Guelph

Program:

Accelerate

Biomolecular Quantitation and Structure Analysis to Accelerate Development of New Vaccines

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of biologic products which, relative to small molecular drugs, have a larger size, are more complex in structure and are thus more difficult to characterize. Modern instrumental analyses, including Mass Spectrometry, Nuclear Magnetic Resonance and Capillary Electrophoresis, are capable of high resolution and precision analyses of primary and higher order biomolecule structures and quantitation. Using these cutting-edge technologies, we are proposing to develop new methodologies to improve biomolecule characterization. TO BE CONT’D

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Faculty Supervisor:

Yi Sheng

Student:

Rahima Khatun

Partner:

Sanofi Pasteur

Discipline:

Biology

Sector:

Pharmaceuticals

University:

York University

Program:

Accelerate

Understanding the Millennial Sports Fan

Millennials are a large, tech savvy demographic that media companies are expending significant resources to connect with and market to. This project will develop a comprehensive understanding of the sport media consumption habits of Canadian Millennials, aged 18-24, using surveys and other methods being employed by researchers across the country. Understanding Millennials consumption patterns and behaviours is of paramount importance to sport media companies. The industry partner, Rogers Sportsnet, well benefit from this project because the results will allow it to assess its investments in sport media properties and the resonance of its media engagement with Millennials.

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Faculty Supervisor:

Cheri Bradish

Student:

Mark Norman

Partner:

Rogers Sportsnet

Discipline:

Business

Sector:

Media and communications

University:

Ryerson University

Program:

Accelerate

Probiotics Alleviating Depressive Symptoms (PADS)

Recent evidence shows there is extensive and direct communication between the brain and gastrointestinal tract, where nutrients are absorbed, and that intestinal microbiota have a role in healthy brain function. This study aims to look at the effects of probiotics, live bacteria that inhabit the gut and can help improve your health, on the mood, cognition, and sleep of depressed patients. We hypothesize that by increasing the integrity of the gastrointestinal wall, probiotics reduce the amount of toxins leaking out into the bloodstream, thus reducing overall levels of inflammation, which are increased in the brains of depressed patients. If shown to be effective, these results could have a major impact for those seeking antidepressant treatment and allow them to use basic nutrition to help improve their symptoms and an lead to an increase in the development and demand of more natural treatment approaches.

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Faculty Supervisor:

Roumen Milev

Student:

Caroline Wallace

Partner:

Lallemand Health Solutions

Discipline:

Psychology

Sector:

Medical devices

University:

Queen's University

Program:

Accelerate

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