Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

30508 Completed Projects

2882
AB
5105
BC
825
MB
681
NL
860
SK
9051
ON
9491
QC
97
PE
586
NB
1141
NS

Projects by Category

Genomics profiling of peritoneal mesothelioma and patient-derived xenograft models for in vivo biomarker validation

Peritoneal Mesothelioma (PM) is a rare type of cancer affecting the protective membrane surrounding the abdominal cavity and the second most common type of mesothelioma, consisting about 10-20% of the diagnosed cases. The underlying cellular and molecular mechanisms of peritoneal mesothelioma pathology are greatly understudied. In this proposal, we aim to enhance the current knowledge of PM pathogenesis and explore therapeutic treatments for it. To this end, we aim to establish a working group that combines pertinent and unique expertise in the areas of surgery, pathology, genomics, xenografting and biology. This collaborative team of researchers will collect and perform a pathology review on an initial cohort of PM tissues with good clinical records using state-of-the-art high-throughput DNA, RNA, and protein sequencing. We also aim to generate an in vitro PM patient-derived xenograft mouse model that can recapitulate the tumor in vivo for drug screening and testing for safety, response, and efficacy in collaborations with our biotech partner.

View Full Project Description
Faculty Supervisor:

Yuzhuo Wang;Colin Collins

Student:

Partner:

BC Cancer Foundation;iProgen Biotech Inc

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

The University of British Columbia

Program:

Accelerate

Intraoperative optical characterization of brain tumor tissues

The goal of neurosurgery are two folds, 1) to achieve maximal resection of the target lesions, but simultaneously 2) minimize damage to adjacent healthy brain tissues. Currently surgeons rely on preoperative images such as Magnetic Resonance Imaging to define tumor boundaries. However, the accuracy of such images decreases intraoperatively due to brain shift. For these reasons, surgeons tend to be conservative during tumor resection resulting in residual brain tumors being left behind and thereby increasing the risk of tumor relapse. In this study, we will investigate Raman Spectroscopy (RS) and Polarization Sensitive Optical Coherence Tomography (PSOCT) as novel intraoperative brain imaging tools. Both RS and PSOCT are label-free, rapid, and nondestructive modalities. RS images the chemical make-up of tissues while PSOCT images the structure of tissues. We will investigate whether RS can consistently distinguish tumor from non-tumor tissues and whether PSOCT can visualize structured nerve fibers in situ.

View Full Project Description
Faculty Supervisor:

Taufik Valiante

Student:

Partner:

Synaptive Medical Inc

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Manufacturing; Professional, scientific and technical services

University:

University of Toronto

Program:

Accelerate

DFT calculation of H abstraction reactions of phenyl-?-naphtylamine with alkyperoxy radicals

Lubricating oil degradation is a ubiquitous problem in industrial machinery. In general, this process includes the thermal breakdown, oxidation, and polymerization of the oil molecules as they turn into undesirable by-products while the lubricant ages. Primary antioxidants, also known as radical scavengers, are regularly added to the lubricant to remove the initial peroxy
and alkyl radicals. As a large number of industrial applications rely on the use of such additives, it is therefore very important to have solid knowledge of the efficiency of each type of antioxidant molecule. This project will use density functional theory (DFT) to look at a sample of three Habstraction reactions between a popular antioxidant molecule, phenyl-?-naphtylamine and a series of alkylperoxy radical molecules. These results will be used by our partner organization, GasTOPS Ltd., to refine a thermochemical model of the oil degradation process. This will allow GasTOPS engineers to design more accurate macroscopic models of the oil breakdown in industrial setups.

View Full Project Description
Faculty Supervisor:

Ronald Miller

Student:

Partner:

Gastops

Discipline:

Physics

Sector:

Aerospace; Technology; Oil and Gas

University:

Carleton University

Program:

Accelerate

Développement et optimisation de procédés de production de 2 cutinases pour applications industrielles

Le but général est de favoriser la commercialisation de deux enzymes de type cutinase en développant des procédés de production/purification prometteurs et d’intérêt industriel. Les cutinases sont des enzymes intéressantes pour l’hydrolyse de divers corps gras et de certains plastiques, ainsi que pour la modification de surfaces. Pour chacune des cutinases, cinq (5) objectifs spécifiques ont été définis, couvrant les aspects production par fermentation, postproduction, et mise en oeuvre des enzymes. Ce projet permettra au partenaire industriel de développer diverses applications pour ces enzymes dans les domaines suivants : nettoyage et hygiène dans les secteurs industriel et médical & biotransformation ou dégradation de mycotoxines pour une alimentation animale sécuritaire et de plus haute qualité.

View Full Project Description
Faculty Supervisor:

Denis Groleau

Student:

Partner:

Ozymes

Discipline:

Engineering

Sector:

Biotechnology; Agriculture and Food; Environmental Science and Technology

University:

Université de Sherbrooke

Program:

Accelerate

A new paradigm for the discovery of anti-cancer drugs based on tumour RNA disruption

While chemotherapy drugs are effective in combating tumour growth in cancer patients, many such drugs permit the development of drug-resistant tumours and progression of the disease. We have observed that several chemotherapy agents induce the degradation of tumour cell ribonucleic acid (RNA) in the laboratory and in cancer patients. We have further shown that this RNA degradation is associated with complete tumour destruction after-treatment. Our recently developed assay to quantify RNA degradation in tumour cells may thus prove to be a very sensitive, quantitative, high throughput, and preferred method for the discovery of anti-cancer drugs that will commit tumours to complete destruction. The study to be performed by the intern will assess this hypothesis in comparison to the current “gold standard” for anti-cancer drug discovery (the “clonogenic” assay).

View Full Project Description
Faculty Supervisor:

Carita Lanner

Student:

Partner:

RNA Diagnostics Inc

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Professional, scientific and technical services

University:

Laurentian University

Program:

Accelerate

Ecological and Cultural Restoration of an iconic Plant Food (Fritillaria camschatcensis) in the Squamish River Estuary, British Columbia

I am a member of the Squamish Nation and my research focuses on restoring an important traditional plant food into the Squamish estuary. The title of my research is “Ecological and Cultural Restoration of an iconic Plant Food (Fritillaria camschatcensis) in the Squamish River Estuary, British Columbia.” I will be working with Dr. Nancy Turner and Dr. Trevor Lantz as my co-supervisors at the University of Victoria to undertake this research as part of a larger research project led by Dr. Turner called “Bringing the Foods Home” that focuses on renewing traditional foods in Indigenous communities. My research will focus on conducting an ecological survey of the Squamish estuary to characterize successful riceroot habitat and then to construct an experimental garden where this plant can be tended to and used for educational purposes. I will incorporate community involvement throughout this research and emphasize the link between traditional foods and health.

View Full Project Description
Faculty Supervisor:

Nancy Turner

Student:

Partner:

Discipline:

Earth science

Sector:

Public administration

University:

University of Victoria

Program:

Accelerate

Identification of early events involved in RNA disruption in order to improve its utility as a chemotherapy response and prognostic biomarker

It is not well known that the majority of breast cancer patients do not receive a survival benefit from chemotherapy. Yet, they experience many negative short- and long-term side effects from chemotherapy. This is also the case for other cancers. There is thus a clear, unmet need for a diagnostic tool that can reliably identify chemotherapy nonresponders, so that they can be moved quickly to potentially more beneficial treatments, while sparing the toxicities of the ineffective drugs. We have developed an effective tool (RDA) to assess chemotherapy response in cancer patients, based on the ability of chemotherapy drugs to induce the degradation of ribonucleic acid (RNA) in tumours. This project seeks to better understand the mechanisms by which chemotherapy drugs promote RNA degradation. By identifying earlier events that trigger RNA degradation, we expect to improve our ability to predict chemotherapy response in cancer patients, possibly much earlier after chemotherapy
administration.

View Full Project Description
Faculty Supervisor:

Carita Lanner

Student:

Partner:

RNA Diagnostics Inc

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Professional, scientific and technical services

University:

Laurentian University

Program:

Accelerate

Cross-sector partnerships for implementing sustainable community plans: comparison between a Canadian city and international communities to determine drivers for partners to remain in the partnerships

The project involves the identification of a Canadian community to be compared with Barcelona (Spain), Bristol (UK) and other two international communities, all experienced cities on sustainability with more than 100 partners including businesses, NGOs, academia and the public sector. The Canadian community must comply with certain criteria to make findings comparable with the international communities. The information to be collected is about the drivers for the partners to join
and remain in a partnership for sustainability, a key for policy makers and practitioners in the design of sustainability plans and partnerships for reaching sustainability goals. ICLEI Canada will benefit from this research by having access to information from four highly recognized communities and by comparing them to one of its members as a benchmark for the improvement of their sustainability initiatives. Furthermore, the findings will be generalizable information that will help improve their products and services.

View Full Project Description
Faculty Supervisor:

Amelia Clarke

Student:

Partner:

ICLEI Local Governments for Sustainability

Discipline:

Sociology

Sector:

Professional, scientific and technical services; Public administration

University:

University of Waterloo

Program:

Accelerate

A Survey of Ergonomics Education Opportunities Available to Dental Hygienists in Ontario.

Dental hygienists (DH) are exposed to many potentially injurious physical demands, such as prolonged exposure to awkward neck, trunk, and shoulder postures. The prevalence of musculoskeletal disorders in this group is alarmingly high (62-93%). DH would benefit from ergonomics-specific workplace safety education, but it is unknown what sort of instruction, if any, is currently offered within the DH curriculum or for continuing education credit. Evaluation of existing educational opportunities will be conducted using a web-based survey of DH across Ontario. The surveys will also include questions regarding the mode of continuing education the DH would find most accessible (e.g. online or night courses, workshops, etc.). The results of the
survey will guide ergonomists at the Occupational Health Clinics for Ontario Workers Inc. in updating existing and/or creating new educational resources for registered DH and DH programs, in order to promote proactive injury prevention in this occupational group across the Province.

View Full Project Description
Faculty Supervisor:

Nadia Azar

Student:

Partner:

Occupational Health Clinics for Ontario Workers Inc

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

University of Windsor

Program:

Accelerate

Stock assessment in a changing world: quantifying the length of time series data for reliable stock assessments of Lake Whitefish in the Great Lakes

Lake Whitefish (Coregonus clupeaformis) are currently the subject of research to obtain Marine Stewardship Council certification for the fishery in Lake Erie. The declines of Lake Whitefish stocks in Lakes Huron, Erie and Ontario have drawn much concern from the fishing industry, regulators, and other stakeholders. Better estimates of the stock status are needed to understand the causes of this decline and to facilitate more sustainable management of these stocks. My project aims
to assess Lake Whitefish stock status by 1) selecting appropriate stock assessment models for Lake Whitefish from a literature review, 2) estimating the stock abundance by fitting selected models to time series data to determine the optimal length that minimizes effects of errors generated from surveys versus ecological processes, and 3) providing advice on future research priorities among improvement of survey techniques, determination of ecological mechanisms responsible for stock dynamics, or both.

View Full Project Description
Faculty Supervisor:

Thomas Nudds

Student:

Partner:

Ontario Commercial Fisheries Association

Discipline:

Life Sciences

Sector:

Agriculture

University:

University of Guelph

Program:

Accelerate

Experimental Study on Vectorbloc Connection Used in Modular Construction

Modular construction has been gaining its popularity and momentum because it is a cheaper and faster way to build buildings and other structures. Vectorbloc Corp., located in Toronto has developed the concept of steel tubular modular construction using hollow structural steel (HSS) members. This modular construction will use various connectors and assemblies. The primary connector to be used in the HSS-based modular building construction is called Vectorbloc connector which is a cast-steel connector that facilitates the efficient design and construction of volumetric modular steel building structures. This research will undertake full-scale tests on Vectorbloc connections to be used in modular constriction. Various load combinations will be applied to simulate axial loading on the Vectorbloc connector. These tests will be undertaken in the structural engineering testing laboratory newly built at the University of Windsor and test data will be used to validate the concept modular construction developed by Vectorbloc Corp.

View Full Project Description
Faculty Supervisor:

Sreekanta Das

Student:

Partner:

VectorBloc Corp

Discipline:

Engineering

Sector:

Construction and infrastructure

University:

University of Windsor

Program:

Accelerate

Profil, pratiques et comportements alimentaires d’usagers de Moisson Montréal

L’insécurité alimentaire touche une partie importante de la population montréalaise (16,2%) plaçant la ville au 2e rang des villes canadiennes en matière d’insécurité alimentaire. Afin de contribuer à l’allègement de cette situation préoccupante, Moisson Montréal (MM) offre des services de partage de denrées alimentaires et autres denrées de nécessité à la population montréalaise par l’entremise d’une multitude d’organismes qui se chargent de l’utilisation de ces denrées à bon escient. Dans un but d’optimisation des activités de MM et des organismes récipiendaires ainsi que la bonification des services offerts aux bénéficiaires primaires, soient les familles et individus montréalais, ce projet de recherche mené en partenariat entre le Département de nutrition de l’Université de Montréal et Moisson Montréal se propose d’étudier les pratiques courantes en
matière de sécurité alimentaire et d’identifier celles, parmi elles, qui contribuent à l’allègement et, éventuellement, à la résolution du problème d’insécurité alimentaire à Montréal.

View Full Project Description
Faculty Supervisor:

Malek Batal

Student:

Partner:

Moisson Montreal

Discipline:

Sociology

Sector:

Health and Related Sciences & Technology

University:

Université de Montréal

Program:

Accelerate

Previous
1…315316317318319320321…2,543
Next

Join a thriving innovation ecosystem.

Subscribe to our newsletter now!

Subscribe