Decision-making frameworks for Health Technology Assessment (HTA) have become a major topic in developed nations in recent years. Indeed, the quest for more rational and transparent HTA decision led many jurisdictions to investigate the use of Multi-Criteria Decision Analysis (MCDA) as an alternative decision-making framework. In Canada, the development of a MCDA framework for HTA […]

Poster Digital Networks is a startup Ontario company seeking to install an architectural video-wall display having a large and continuous viewing area. Ruben Barbosa of Poster Digital Networks has extensive display experience in installing and maintaining displays in professional commercial venues. Requirements of a suitable display include high resolution, ease and convenience of calibration, and […]

The main objective of this project is to a) investigate feasibility and suitability of a new proposed DC-DC converter based on a novel “Dual Input Clamp Unidir DC-DC Converter”, and b) validate and quantify its projected benefits including reduced parts count, higher efficiency, lighter weight and more reliable as compared to existing commercial products. Cost-effective, […]

Patients who have hemophilia, a rare blood clotting disease, often have to make important decisions about different treatments for their condition. Research studies have shown that if patients and their health care providers communicate openly about treatment options and preferences and make decisions together, then the chosen treatment can lead to better patient satisfaction and […]

The project aims to address issues in the pricing of interest rate derivatives in an illiquid market. In particular, the project will examine the pricing of options on the Brazilian average interbank deposit rate index. A critical element in determining appropriate prices is the volatility implied by observable market prices. However, the lack of liquidity […]

This research project entails the development and user study assessment of a prototype participatory urban planning tool for the City of Hamilton (Virtual Hamilton), which integrates GIS data with a 3D virtual city model to facilitate stakeholder visualization, collaboration, content contribution, and communication. In consultation with City of Hamilton ward councilors and urban renewal, planning […]

Ontario Early Years Centres (OEYCs) offer programming for young children (0 to 6) and their families. In Hamilton, there are five different OEYCs. The City of Hamilton helps the OEYCs with their planning and with assessing how their programs are helping families. This is complicated, because each OEYC keeps its own data. This project will […]

We propose a meta-analytic project which aims at summarizing Post-Authorization Surveillance Safety data on Advate, a recombinant FVIII concentrates used to treat patients with Hemophilia A. The study will involve the largest cohort of hemophilia patients on FVIII concentrates analyzed in the literature. The project represents an attempt to sustain a methodologically strong approach in […]

The intent of this project is to reduce the cycle time in the vehicle repair process across the Carstar network. The project also includes developing process models that will help in guiding Carstar to reduce cycle time in major process steps for all stores of varying size and disparate locations. During the process of investigation […]

Although early clinical trials have been positive, peptide vaccine mechanism of action (how tolerance is induced) is unknown. The primary objective of these studies is to identify changes in gene expression and cytokine expression that are correlated with vaccine treatment. These changes could provide insight to mechanisms of action and may reveal potential genetic biomarkers […]

The sponsor company, Tigercat specializes in the design and manufacturing of premium quality forestry equipment and specialized off-road industrial equipment. This four months internship project will provide the company a set of load cases validated on a new design, optimized detail 3D and 2D models, selected material lists, and FEA simulation results of a tracked […]

Health economic evaluation compares the associated costs and the clinical outcomes of multiple treatment alternatives and is presently used by payers as one of the many types of evidence to inform which drugs to fund. Given existing health-care budgetary constraints, payers are increasingly interested in knowing whether a new health technology will provide value (i.e. […]