Development of a biosensor for high-throughput screening of novel ezrin inhibitors for treatment of metastatic breast cancer.

Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in […]

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Integrating the User Perception and Experience into the Planning of Automated and Connected Electric Shuttle Services in Canada

The project will provide an opportunity to address key challenges related to user expectation of Automated and Connected Electric Shuttles. That is, the project will serve to advance the understanding of user perception and experience of smart shuttles in Canada. This technology is increasingly often being tested in pilots across Canada and it is critically […]

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Conceptual study of the techno-economic effects of straight drilling on mining operations

Conventional mining activities are composed of four distinct operation coming together. These operations are called; drilling, blasting, loading and hauling. As being the first step in this chain of operations, drilling quality and preciseness is very vital for the success and effectiveness of remaining components. Accurate drilling not only saves time to the company but […]

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Developing the use of UAV Imagery Systems for Agriculture Applications

During the last decade, Unmanned Aerial Vehicles (UAVs) drew the attention to be used as platform for imagery systems for different applications including agriculture applications. Therefore, the proposed research aims to develop the use of UAVs for specific important agriculture applications as weed management. These developments include the use of low-cost imagery sensors for these […]

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Comparing the value of country foods with other food provisioning systems in Indigenous communities in the Northwest Territories.

How can we describe and value harvesting, processing and sharing (costs as well as benefits) country foods in economic, nutritional, environmental and socio-cultural terms? How can we compare the value of country food with food that comes from other provisioning systems (e.g. imported/market-based foods and local food production)? These are important questions for both communities […]

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Predictive Control Approach to Convert Single-Zone Residential Buildings with Central HVAC Systems to Multi-Zone Systems

The current project aims to develop a novel energy management strategy for residential heating ventilating and air conditioning (HVAC) systems. Controllable wireless air damping vents will adjust the air flow in different zones of the building allowing independent control of the temperature which results in enhanced thermal comfort and energy savings. The intern will collaborate […]

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Laboratory and field scale biodegradability assessment for Pela case products for environmentally end-of-life management

Pela, incorporated under Open Mind Development Corporation (OMDC), manufactures environmentally sustainable products, such as compostable smartphone and laptop cases. Pela aims to lead the industry in taking complete responsibility for its manufactured products and continuously improve their lifecycle so that they have the most renewable and sustainable beginning of life, and the most graceful end […]

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Dental Materials for Ultra-Long-Term Caries Prevention

Tooth decay (dental cavities or caries) affects over 90% of the population worldwide, however their treatment with “white” resin composite fillings yields significantly worse results than classic metallic fillings. Caries-causing bacteria penetrate the space between tooth and filling, causing further tooth decay. This damage must be treated by removing the previous filling and diseased tooth […]

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Portable sensor for rapid and onsite detection of bacteria in water

The presence of harmful bacteria in drinking water sources can seriously harm the population that receives the contaminated water. The current standard methods for testing drinking water for bacteria heavily rely on using central laboratories. For small rural communities that are far from these laboratories, this scheme may represent 2-7 delays until they find out […]

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Automation of Low-Energy Welding Process for Aerospace Applications and Contactless Approach

Mechanical failure is a significant issue in the aerospace industry. High material and manufacturing costs make the component repair an attractive option, avoiding the need to scrap parts when defects are detected. Low Energy Welding (LEW) is a micro-welding process that offers several advantages in repairing sensitive high-cost components. Extensive work has been carried out […]

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