Combustion at microscales

Objectives: The proposed research program aims at studying the generation and propagation of unsteady compressible flow phenomena, with chemical heat release, at millimeter and sub-millimeter scales. Based on these findings, a number of biomedical and aerospace applications will be pursued in the area of high-power density microsystems. Scientific approach: Our approach is based on the […]

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The duty to vote

From a purely utilitarian perspective, voting does not appear to be a ‘rational’ choice in a large electorate election if there is some opportunity cost in going to the polls, given the extremely low probability that one’s decision will be pivotal (Owen and Grofman 1984; Mueller 2003). Yet most people vote, which is known as […]

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Dynamics and Control of Quadrotor Vehicles

Research and development of small UAVs have accelerated over the past few years, spurred on by the progress in miniaturization of actuator, sensor and computer control technologies. A number of such UAVs are currently available commercially and many more have been developed by researchers for laboratory studies. The focus of the present project is on […]

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Molecular mechanisms of synapse remodelling

In the CNS the majority of excitatory synapses are formed onto specialized structures known as dendritic spines which can undergo shape changes in the time frame of minutes to days. This inherent structural plasticity of dendritic spines even lasts into adulthood. It is still unclear why certain spines are more likely to be maintained, to […]

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Climate change adaptation policy and practice: country case-study

The project will focus on a case-study of adaptation across scales in a single country (likely the applicant’s country of origin). The project is guided by the following research questions: What does adaptation look like in regions with limited formal and institutional reporting of adaptation action? In these regions, is adaptation absent, or is it […]

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Global Special Interest Group (SIG) on Early Identification and Intervention in Autism

The project title is the Global Special Interest Group (SIG) on Early Identification and Intervention in Autism. Formed in 2012, the aim of this project is to enhance research impact in diverse communities through the iterative and dynamic process of knowledge translation: the synthesis, dissemination, exchange, and application of knowledge to improve quality of life […]

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Statistical Analysis and Modeling of Vaccine Manufacturing Process Applied to Cell-Culture Based Adenovirus Vaccine

This project intends to research vaccine manufacturing process from a broader perspective and apply Quality by Design (QbD) concepts to develop a robust novel process for commercial vaccine production. To implement QbD principles, the impact of several process parameters (including cell density, pH, temperature, and harvest time) on the Critical Quality Attributes (CQAs) of the […]

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Optimizing Fibre Flow in the Forest Products Industry

FPInnovations has developed FPInterface, a software platform in which forest operations are simulated in order to estimate fibre supply costs, including harvesting and transportation. It currently has 7 sub-modules including MaxTour and FPAlloc. The goal of this project is to develop and validate optimization techniques in order to implement new sub-modules to FPInterface that will […]

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Development of novel biochemical and biophysical assays for the identification of inhibitors of Hypoxia Inducible Factor-2

Cancer cells are known for their unique capacity to survive and grow in a low oxygen tension environment in the middle of a poorly vascularized solid tumor. This adaptation, which is central to the tumorigenesis process, is mediated by precise cellular mechanisms allowing the regulation of gene expression. Thus, the development of small molecules to […]

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Machining process monitoring at PWC by using machine learning and advanced artificial intelligence techniques

Pratt & Whitney Canada (PWC) seeks to improve the monitoring of its machining process aiming to reduce cost and prevent the tools, workpieces and machine damages during the machining. To achieve this improvement, data mining and advanced artificial intelligence technique which called Logical Analysis of Data (LAD) is used. LAD has ability to identify conditions […]

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Network Function Virtualization (NFV) Driven Micro Service Architecture for Value Added Video Streaming Services in Content Delivery Networks

The NSERC Strategic Network for Smart Applications on Virtual Infrastructures is a five-year partnership between Canadian industry, universities, researchers, research and education (R&E) networks, and high performance computing centres to investigate the design of future application platforms that will deliver software applications of greater capability and intelligence. These application platforms will be supported by an […]

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