Xenon has developed isoform selective blockers of the sodium channels that are expressed in CNS neurons with the intent of developing them for therapeutic use, especially epilepsy. The primary goal of this research project is to determine the activity of compounds on CNS neurons. Until now, all characterization has been done with heterologously expressed channels. […]

The “Fearless Physical Activity” workshops are designed to educate and introduce children with congenital heart disease (CHD) to physical activities that are safe for their health. These workshops will provide opportunities for children with CHD and their families to try new activities and to learn about the benefits of lifelong physical activity, specific to those […]

“Lifeguard Health Networks Inc. (LHN) has developed a secure Virtual Health Assistant application (app), to enhance supported self-management for patients with chronic and complex conditions, by leveraging their network of trusted family and friends, under the direction and guidance of health practitioners.We are conducting a study to evaluate the feasibility of the app and the […]

Infertility is a health issue that affects over half a million Canadian of childbearing age. Half of these cases are related to male reproductive dysfunctions. While semen analysis provides information about some causes of male infertility, about thirty percent of these cases remains unexplained. In this context, the main goal of our project is to […]

Prostate biopsies can be difficult to interpret using standard pathology techniques. Because cancer can be fatal, the development of technologies providing complementary information could improve current pathology practice resulting in improved patient outcome. Raman micro-spectroscopy is a molecular imaging technique using backscattered light following tissue laser excitation to indicate whether or not prostate samples contain […]

The purpose of this research is to validate the Functional Resilience Question-Air (FRQ; Kinley, 2016), an assessment tool based on scientific principles that use the latest research on resilience and neuroplasticity. Specifically, the Functional Resilience Question-Air identifies employees’ personal strengths, providing them with a global resilience score as well as a personalized development plan. Designed […]

A critical challenge today in neuro-surgery is the determination of tumor boundaries intraoperatively. There are means of doing this using high-resolution MRI machines, however, these can be prohibitively costly. Optical coherence tomography (OCT) offers a promising, cheaper, label-free alternative. However, the basic models used for clinical, real-time OCT limit its usefulness and depth of focus. […]

Over 14 million Canadians live with overweight or obesity. Patients want conversations with their primary care team about weight and create personalized plans to improve their health. Primary care clinicians want to have these conversations too, but don’t know how. This project partners with an interdisciplinary primary care team (ESPCN) and the Canadian Obesity Network […]

AF is an irregular heart rhythm resulting from abnormal electrical impulses and is the most common cardiac arrhythmia encountered in clinical practice. Ablation therapy has been used to eliminate areas responsible for maintaining the arrhythmia using radiofrequency energy. Targeting the culprit regions usually require accurate estimation of activation times in IEGM recordings. The conventional time […]

Currently available diagnostic imaging tools, such as chest radiography and computed tomography, are inadequate for assessing the lungs of preterm neonates. There is considerable interest in using magnetic resonance imaging (MRI) to monitor lung development in neonates longitudinally, since it is a non-invasive and non-ionizing imaging modality. MRI can potentially detect complications at an early […]

Medication errors are common in long-term care homes, as older adults are at an increased-risk of experiencing medication errors. Additionally, most older adults living in long-term care homes have dementia, and few can identify themselves; this increases the risk of a medication error. Tap2Tag Medical Ltd. offers the Tap2Tag Medical Alert Bracelet. The bracelet encompasses […]

The aim of the internship is for the intern to take up the challenge of detecting and removing noise from brain signals that are recorded using electroencephalogram (EEG). The noise that is of interest in the project is mainly caused by the subject chewing and walking. These noises are found to have caused the inability […]