A filter cartridge for removal of drugs and estrogens from drinking water

The research problem to be addressed in this project concerns the need for advanced water filtering systems that will remove traces of pharmaceuticals and estrogen hormones from drinking water. This problem is significant because these contaminants, that enter water as a result of human use, have been found in river water, treatment plant effluents and […]

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Radiofrequency Treatment for Emphysema in Rat Model

Emphysema, a lung disease that millions of Canadians currently suffer from, has few safe and non-invasive options available. One of the features of emphysema is the lack of proper blood flow in the diseased lungs and this results in poor gas exchange. IKOMED Technologies Inc. and the two interns will test an innovative technology that […]

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An Optimized Tele-Rheumatology Platform for Clinical Settings

Current rheumatology wait-times have been noted as reaching as high as two years for an initial assessment in the province of Newfoundland and Labrador (NL) [1]. Significant wait-times can delay diagnosis and treatment for a variety of rheumatologic conditions and highlights some of the challenges associated with a publicly funded healthcare system. Furthermore, the higher […]

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Assessing the Utility of a Commercial Mobile EEG in Detecting Age-Related Differences in the Brain – Year two

The world is aging rapidly and healthy cognitive aging a major healthcare priority. Thus, a better understanding of how the brain changes with normal aging versus pathology is required. Advancements in wearable technologies may allow the assessment of brain function with greater ease, accessibility, and at a lower cost, as compared with traditional neuroimaging techniques. […]

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Developing statistical methods to discover genetic variants underlying longitudinal decline in lung function

COPD is a common inflammatory lung condition that is characterized by airflow limitation and symptoms of cough and shortness of breath. Globally, it affects 384 million people and is responsible for ~4-7% of all deaths. Longitudinal genome-wide association studies (GWAS) are needed to unravel the molecular determinants of dynamic quantitative traits underlying COPD, such as […]

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Human kinematic optimal control learning and wearable inertial measurement unit alignment for rehabilitation

Physiotherapy is a type of rehabilitation that aims to restore a patient’s quality of life after an injury, surgery, or stroke by improving their mobility. Through prescribed exercises and specialized equipment, physiotherapy helps the patient to regain their muscle strength, range of motion, and natural movement. Unfortunately, only rudimentary tools are available to the therapists […]

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Understanding the effect of the oral microbiome on the performance of dental implant crown materials

We are at the era of precision medicine and dentistry; however, currently there have been no attempts for personalized dental implant design and material selection that take into account variations in individuals’ anatomy, oral microbiome, saliva properties, and mechanical requirements. The overall objective of this MITACS project is to utilize a multidisciplinary approach to explore […]

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A Feasibility Study of a Measure of Resiliency in a Vulnerable Population

Managing daily life can be overwhelming when living with low income, mental illness, addiction, and social isolation/discrimination. When crises occur, intergenerational cycles of trauma can result. Social support and strength can be found in families and support systems, but these are often not ideal. This research project will result in a measurement of resiliency in […]

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The potential effects of a carbonic anhydrase IX (CAIX) inhibitor, SLC-0149, on AD pathogenesis

Alzheimer’s disease (AD) is the most common neurodegenerative disorder. SignalChem LifeSciences Corp. recently developed a potent small molecule inhibitor (SLC-0149) for targeting CAIX, a hypoxia inducible gene, in the application of treating cancers. Since hypoxia has been implicated as a factor to facilitate AD development, this study aims to explore the potentiality of applying SLC-0149 […]

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