Tissue engineering works to replace damaged tissue and organs, and has applications in treating diseases such as diabetes. To improve the performance of tissue engineering treatment and research, our lab has produced the microwell system which creates microtissues in the form of cellular balls. The microwell system has been used used internationally under the brand […]

The recent legalization of marijuana in Canada opens the opportunity to study in detail the effects of cannabinoids on human physiology. This academic-industry initiative will combine resources to isolate compounds from cannabinoids to study their effects on bone cells. Specifically it will examine the effects of cannabinoid compounds on how the destructive osteoclasts form and […]

Occupational stress conveys risk of Posttraumatic Stress Disorder (PTSD). In PTSD, early diagnosis and early treatment interventions are advantageous for positive outcomes. We will develop novel technology for early diagnosis of and prediction of vulnerability to PTSD in military and first responder personnel. Based on our existing collaboration on identification of symptoms and prediction of […]

We recently developed a rapid and cost-effective pre-clinical technology that is well suited for precision medicine –the ex ovo chicken embryo ChorioAllantoic Membrane (CAM) assay. Our goal is to perform a pilot study that combines tumor genotyping data and the use of personalized CAMavatars, to predict drug sensitivity in renal cancer patients and to test […]

The Canadian Institute for Military and Veteran Health Research (CIMVHR), affiliated research partners at universities across Canada, and IBM Canada Ltd. have identified a significant and universal issue facing health researchers that applies to Canadian military, Veteran and family health (MVFH) research and health research for the Canadian population at large. Comprehensive and complete medical […]

Funds are requested for one fellow to work in the laboratory of Dr. Simon Graham at Sunnybrook Research Institute, Toronto, in partnership with Siemens Healthcare Limited. The fellow will work on development of prototype instrumentation that will enable a technique called “parallel radiofrequency transmission (PTX)” to be implemented flexibly for research purposes on a Siemens […]

Alzheimer’s disease (AD) is a neurodegenerative disorder that is difficult to detect early before apparent manifestations of cognitive decline. Current detection methods rely on expensive and hardly accessible imaging techniques (PET scans). Optina Diagnostics developed a new camera as well as innovative image processing methods to propose a non-invasive test to identify the presence of […]

Across Canada, many families struggle to find high quality, affordable child care. Most child care options for families are limited to daytime and weekday work hours; this creates even greater challenges for shiftworkers who rely on paid child care. When child care is not available, mothers usually bear the greatest burden as many women, whether […]

The recent advances in machine learning based on deep neural networks, coupled with the availability of phenomenal storage capacity, are transforming the industrial landscape. However, these novel machine learning approaches are known to be data hungry, as they need to tune a huge number of parameters in order to perform well. As more and more […]

Histopathology is the study and examination of tissue slides under magnification and is the definitive diagnosis for many diseases including cancer. With the advent of whole-slide scanners and image management software systems, computational pathology tools can be created to measure disease in an efficient and objective manner. This is in contrast to the labourious and […]

The main goal of this project is to design a UAV-based image acquisition system to capture high quality full body images which will be integrated into DermEngine Full Body Imaging (FBI) module. With this system, we intend to achieve consistency between different images that FBI needs to analyze. We also plan to deliver an easy-to-use, […]

For patients with end-stage disease, like cirrhosis, their only treatment option is life-saving organ transplantation. The wait for an organ can take many years over which the patient’s condition continues to deteriorate as there is no other treatment. However, maintaining physical activity and a good nutritional intake is necessary to remain on the wait and […]