Nicotine is a highly addictive chemical and smoking is still, to this day, the leading cause of preventable death. Several pharmacological strategies have been approved for smoking cessation and nicotine addiction treatment. However, these strategies are not always effective and lead more often than not to relapse. Hence, new nicotine cessation products and devices are […]

The goal of this study will be to development a process to manufacture the oil-based raw material with PAT implementation.

Le but de cette recherche est d’améliorer les propriétés thérapeutiques d’un produit sanguin qui peut sauver des vies des patients avec une infection sévère due à un système immunitaire affaiblie. Ces patients ont un nombre insuffisant de neutrophiles ou des neutrophiles qui ne fonctionnent pas très bien. Les neutrophiles sont des globules blancs qui jouent […]

The aquaculture industry is growing rapidly worldwide and provides job opportunities as well as food for humans. However, diseases that are bacterial or viral, having a devastating effect on this sector. Every year huge economic losses are occurring due to bacterial diseases. Though there are several commercial vaccines available on the market, their efficacy is […]

Within the realm of transition metal-catalyzed reactions, considerable interest lies in the ability to generate carbon-carbon linkages using cheap and abundant catalysts and reagents, as products derived from these couplings are widespread amongst bioactive molecules including pharmaceutical and agricultural agents. The importance of catalyst design in facilitating particularly challenging couplings of this type cannot be […]

The project aims to facilitate the research and development of new drugs by applying machine learning and deep learning to further develop an AI-assisted molecular search database. The company has an internal dataset holding more than a billion molecules. Two main challenges are keeping the molecule catalog updated and Searching for the desired molecule or […]

Les troubles musculosquelettiques (TMS) sont une préoccupation importante au Québec et diverses avenues de prévention sont mises de l’avant pour en diminuer leurs impacts : formation du personnel, conception d’aménagements et/ou d’équipements adaptés, ajustement des exigences de production, etc. Dernièrement, les exosquelettes semblent susciter l’engouement pour prévenir ces risques dans les milieux de travail. Cependant, […]

Molecular generative methods are at the heart of our computational platform. We use cutting edge deep neural networks in order to generate unseen molecules based on existing conditions or molecular space. Since external projects typically require different architectures, we are continuously expanding our generative methods toolbox with new approaches. This project aims to augment our […]

Le cancer de la bouche fait partie de la maladie maligne du carcinome épidermoïde de la tête et du cou, qui constitue un grave problème de santé publique en raison de son incidence, de sa prévalence et de sa mortalité élevées (Moro JDS et al., 2018). Il est classé au 6e rang mondial des tumeurs […]

Over the last several decades, challenges in the development, production, supply, and use of vaccines have been raised and by consequence had led to increasing concern around the world. As a result, an increase in research and innovation in the vaccine industry is needed. In this sense, one of the most critical factors in the […]

The global burden of hepatocellular carcinoma (HCC) is increasing as it has become the second leading cause of cancer-related deaths and the fifth most common cancer worldwide. HCC is heterogenous, arising in the setting of various chronic liver diseases such as hepatitis C, non-alcoholic fatty liver disease and cirrhosis. Patients with cirrhosis who develop cancer […]

Many drugs, such as those made of antibodies, are produced using cells from bacteria and other organisms. Companies such as BioVectra use this approach to produce antibody drugs efficiently and cost-effectively. At the end of the production process, residue such as protein from the “host” cells (called host cell proteins, or HCPs) must be removed […]