Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

30508 Completed Projects

2882
AB
5105
BC
825
MB
681
NL
860
SK
9051
ON
9491
QC
97
PE
586
NB
1141
NS

Projects by Category

Molecular diagnostics for temperature stress and pesticide stress on queens

Honey bee colony health and productivity is intrinsically linked to the quality of the queen. Unfortunately, queen quality is compromised by stressors such as extreme temperatures and pesticide exposure. When queens are heat- and cold-shocked, the viability of their stored sperm drastically decreases, causing colonies to dwindle, produce less honey, and ultimately fail. Pesticide exposure has similar effects. But we currently don’t have diagnostic tools for identifying root causes of queen failure, so beekeepers are often simply left guessing or wondering why. Some queen tests exist, such as measuring sperm viability from dissected spermathecae, but they have limited practical utility because they still do not identify the underlying cause of viability losses. This project aims to develop molecular diagnostic tests for heat-stress, cold-stress, and pesticide-stress events for queens as a further step towards evidence-based colony management

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Faculty Supervisor:

Leonard Foster

Student:

Partner:

Canadian Honey Council

Discipline:

Life Sciences

Sector:

Agriculture

University:

The University of British Columbia

Program:

Accelerate

Research and Development of Urinary Metabolome-based Personalized Health Assessment for Inflammatory Bowel Disease, Autism and Environmental Exposure – Year Two

Despite the growing interests and publications in metabolomics, there is a significant gap between what have been found through scientific studies and what have actually been applied in clinical practice and preventative healthcare. This proposed project aims to fill this gap by addressing two major causes; 1) lack of utilization in existing metabolomics data and published findings, and 2) lack of an accessible tool to collect samples for metabolomics data at home. The first issue is addressed by text mining of published studies and online databases using machine learning techniques. This is followed by a development of multivariate statistical models based on the extracted data. To address the second issue, this project also focuses on a development of a collection kit and suitable analytical methods for metabolites found in urine, a biological specimen that can be collected non-invasively in large volume at home. This will expand current capability of Molecular You Corporation to acquire new information of human health and perform early diagnosis of various conditions of interest, such as autism and inflammatory bowel disease. This collaboration between the personalized digital health company and the major metabolomics research group is expected to bring impacts of metabolomics research efforts into society.

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Faculty Supervisor:

David S Wishart

Student:

Partner:

Molecular You Corporation

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Professional, scientific and technical services

University:

University of Alberta

Program:

Elevate

Mise en operation participative, Inclusive et creative d’une demarchede co-construction de savolrs sur Ie volet Art social et education populaire des projetsde cooperation et de developpement Internat

La crise de I’eau appelle iJ reconstruire notre vIsion du monde iJ partir d’un rapport
d’interdependance entre les hommes et leur environnement Dans Ie cadre d’une evaluation
qualitative des projets de cooperation et de developpement intemational de ONE DROP et
so us la tutelle de Groupe d’evaluation environnementale et de soutien iJ la restauration
ecologique (G,R,E,B.E), deux doctorants s’investissent dans une recherche-action
interdisciplinaire (art/management) et interuniversitaire (Universite LavaUHEC Montreal). Leur
approche participative, inclusive ~t creative vise I’elaboration de mecanismes d’evaluation
constante permettant aux parties prenantes des projets de rendre compte des initiatives du
volet Art social et education populaire, dans son contexte de lutte contre la pauvrete par
I’acces iJ I’eau. Favorisant la construction collective de savoirs, la recherche renforcera la
collaboration entre Ie milieu universitaire et celui de la pratique privee et contribuera iJ
I’avancement des connaissances en arts, en management, en education et en
developpement durable.

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Faculty Supervisor:

Barbara Bader;Djahanchah Philip Ghadiri

Student:

Partner:

One Drop;G.R.E.B.E. Inc

Discipline:

Sociology

Sector:

Other services (except public administration); Professional, scientific and technical services

University:

HEC Montréal; Université Laval

Program:

Accelerate

Research and Development of Urinary Metabolome-based Personalized Health Assessment for Inflammatory Bowel Disease, Autism and Environmental Exposure – Year One

Despite the growing interests and publications in metabolomics, there is a significant gap between what have been found through scientific studies and what have actually been applied in clinical practice and preventative healthcare. This proposed project aims to fill this gap by addressing two major causes; 1) lack of utilization in existing metabolomics data and published findings, and 2) lack of an accessible tool to collect samples for metabolomics data at home. The first issue is addressed by text mining of published studies and online databases using machine learning techniques. This is followed by a development of multivariate statistical models based on the extracted data. To address the second issue, this project also focuses on a development of a collection kit and suitable analytical methods for metabolites found in urine, a biological specimen that can be collected non-invasively in large volume at home. This will expand current capability of Molecular You Corporation to acquire new information of human health and perform early diagnosis of various conditions of interest, such as autism and inflammatory bowel disease. This collaboration between the personalized digital health company and the major metabolomics research group is expected to bring impacts of metabolomics research efforts into society.

View Full Project Description
Faculty Supervisor:

David S Wishart

Student:

Partner:

Molecular You Corporation;University of Alberta

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Professional, scientific and technical services

University:

University of Alberta

Program:

Elevate

Efficacité énergétique en serres agricoles

Une composante importante de l’alimentation durable, dans le contexte du développement durable, est de mettre le consommateur beaucoup plus près, psychologiquement et physiquement, de la production de sa nourriture quotidienne. En particulier, la culture en serre en climat nordique (ex. Québec, Canada) diminue la distance entre le consommateur et le producteur d’aliments à haute teneur nutritive. Cependant, la consommation d’énergie par ce moyen reste élevée. L’organisme partenaire souhaite bénéficier des développements les plus récentes dans les concepts d’efficacité énergétique et de les incorporer dans la conception de serres pour la culture locale en serre. L’objectif principal est d’évaluer le potentiel pour la minimisation de l’utilisation de l’énergie de haute qualité (électricité et carburants fossiles) dans une étape de préconception d’une serre innovatrice modulaire d’environ 3 000 pieds carrés pour la culture de tomates, sur un terrain se situant à Bishopton, Québec.

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Faculty Supervisor:

Mikhail Sorin

Student:

Partner:

Les Écuries RD S.E.N.C.

Discipline:

Engineering

Sector:

Agriculture

University:

Université de Sherbrooke

Program:

Accelerate

Diversification of atmospheric perils: top-down flood and tropical cyclone models with applications to the (re)insurance industry

Just like the idiom says, to not put all your eggs in one basket, insurance and reinsurance are founded on diversification. Pooling among policyholders, lines of businesses, perils, etc., are typical ways to achieve an adequate level of diversification to lower required capital. However, there are several factors that can act to hamper diversification, even on an international basis: namely the concentration of wealth and population in a few large countries (USA, China), and natural climate phenomena such as El Niño and climate change that both affect many countries. The research project aims to analyze how these factors may affect the reinsurance industry’s capability to diversify risks and thus, its ability to insure losses from natural hazards that are too significant for local insurance companies or governments to assume. As a result of this research, the partner will improve its risk management and long-term solvency, in addition to reduce costs to its clients and enhance their protection.

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Faculty Supervisor:

Mathieu Boudreault

Student:

Partner:

AXA XL;AXA XL (UK)

Discipline:

Mathematics

Sector:

Finance and Insurance; Professional, scientific and technical services

University:

Université du Québec à Montréal

Program:

Accelerate

Perioperative Opioid Usage Quality Improvement [CDTS-PDF2] – Year two

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is more important than ever. Recent advances in machine-learning, combined with approaches to patient-oriented research, provide significant prospects for a learning health system. Such a system could risk-stratify children and adults before surgery, so that pre-habilitation and optimized analgesic combinations can be employed to reduce persistent post-procedural pain. Artificial intelligence-augmented systems will also give clinicians actionable feedback on their practice, so they can learn how to improve their care, reduce their patients’ risk further, and
help them to recover more quickly from their procedure.
Postdoctoral fellows will lead day-to-day project activities and spend significant time working with both our clinical sites (St. Paul’s Hospital and BC Children’s Hospital) as well as industry partners (Careteam and Xerus) who will benefit from their methods expertise, ability to collaborate with clinicians and academic researchers, design, implementation, and evaluation skills.

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Faculty Supervisor:

Matthias Görges

Student:

Partner:

Careteam Technologies Inc

Discipline:

Engineering

Sector:

Health and Related Sciences & Technology; Information and cultural industries; Professional, scientific and technical services

University:

The University of British Columbia

Program:

Elevate

Perioperative Opioid Usage Quality Improvement [CDTS-PDF2]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is more important than ever. Recent advances in machine-learning, combined with approaches to patient-oriented research, provide significant prospects for a learning health system. Such a system could risk-stratify children and adults before surgery, so that pre-habilitation and optimized analgesic combinations can be employed to reduce persistent post-procedural pain. Artificial intelligence-augmented systems will also give clinicians actionable feedback on their practice, so they can learn how to improve their care, reduce their patients’ risk further, and
help them to recover more quickly from their procedure.
Postdoctoral fellows will lead day-to-day project activities and spend significant time working with both our clinical sites (St. Paul’s Hospital and BC Children’s Hospital) as well as industry partners (Careteam and Xerus) who will benefit from their methods expertise, ability to collaborate with clinicians and academic researchers, design, implementation, and evaluation skills.

View Full Project Description
Faculty Supervisor:

Matthias Görges

Student:

Partner:

Careteam Technologies Inc

Discipline:

Engineering

Sector:

Health and Related Sciences & Technology; Information and cultural industries; Professional, scientific and technical services

University:

The University of British Columbia

Program:

Elevate

Using Social Media to Address Misinformation about HPV and Influenza Vaccines: An Intervention on Facebook

Vaccination is a widely accepted public health intervention, yet public confidence in vaccines is affected by misinformation about vaccine safety shared mainly on Facebook. This project aims to increase availability of credible information about HPV vaccines and influenza vaccines on Facebook. It includessix phases: 1) identify the most relevant approaches for marketing campaigns; 2) conduct pre-campaign surveys with parents and health professionals; 3) prepare advertisements to address misinformation; 4) publish advertisements on Facebook; 5) conduct post-campaign surveys to assess the success of the campaigns; 6) assess the relevance of the campaign strategies for long-term outcomes. This study focuses on the phase 2. We will conduct two pre-campaign surveys: one with parents to gather their knowledge and attitudes regarding HPV vaccines and vaccination, and another one with health professionals to gather their knowledge and attitudes regarding influenza vaccines and vaccination. This study will help prepare advertisements addressing misinformation on Facebook.

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Faculty Supervisor:

Kieran O’Doherty

Student:

Partner:

Canadian Public Health Association

Discipline:

Sociology

Sector:

Other services (except public administration); Professional, scientific and technical services

University:

University of Guelph

Program:

Accelerate

Perioperative Opioid Usage Quality Improvement [CDTS-PDF1] – Year two

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is more important than ever. Recent advances in machine-learning, combined with approaches to patient-oriented research, provide significant prospects for a learning health system. Such a system could risk-stratify children and adults before surgery, so that pre-habilitation and optimized analgesic combinations can be employed to reduce persistent post-procedural pain. Artificial intelligence-augmented systems will also give clinicians actionable feedback on their practice, so they can learn how to improve their care, reduce their patients’ risk further, and
help them to recover more quickly from their procedure.
Postdoctoral fellows will lead day-to-day project activities and spend significant time working with both our clinical sites (St. Paul’s Hospital and BC Children’s Hospital) as well as industry partners (Careteam and Xerus) who will benefit from their methods expertise, ability to collaborate with clinicians and academic researchers, design, implementation, and evaluation skills.

View Full Project Description
Faculty Supervisor:

Matthias Görges

Student:

Partner:

Careteam Technologies Inc

Discipline:

Engineering

Sector:

Health and Related Sciences & Technology; Information and cultural industries; Professional, scientific and technical services

University:

The University of British Columbia

Program:

Elevate

Developing rAAV-mediated retinal gene therapy to improve vision for ZellwegerSpectrum Disorder – Year Two

Peroxisome Biogenesis Disorders of the Zellweger Spectrum (PBD-ZSD) are a group of inherited genetic disorders caused by mutations in any one of 13 PEX genes. Individuals with the common PEX1-G843D mutation consistently develop a retinopathy that progresses to blindness. To test whether we could slow visual loss in these patients, we performed a proof-of-concept trial for PEX1 retinal gene augmentation therapy using our mouse model homozygous for the equivalent PEX1-G844D mutation. We found that expression of functional PEX1 in the retina of this mouse model resulted in twofold improvement of retinal function over 6-7 months, and was effective at both earlier and later disease stages. In partnership with AmorChem Therapeutics, we will advance the preclinical, and eventually clinical, development of this therapy. Dr. Argyriou will lead the maturation plan over the 2-year Postdoctoral fellowship. The project includes experiments to establish the optimal design of the clinical gene delivery vector, dose, and efficacy, as well as establishing a business plan towards commercialization. These experiments will lead to safety and toxicology studies in nonhuman primates and an ultimate transition to the clinic.

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Faculty Supervisor:

Nancy Elise Braverman

Student:

Partner:

Amorchem Therapeutics Inc

Discipline:

Life Sciences

Sector:

Finance and Insurance; Professional, scientific and technical services

University:

Research Institute of the McGill University Health Centre

Program:

Elevate

Developing rAAV-mediated retinal gene therapy to improve vision for ZellwegerSpectrum Disorder

Peroxisome Biogenesis Disorders of the Zellweger Spectrum (PBD-ZSD) are a group of inherited genetic disorders caused by mutations in any one of 13 PEX genes. Individuals with the common PEX1-G843D mutation consistently develop a retinopathy that progresses to blindness. To test whether we could slow visual loss in these patients, we performed a proof-of-concept trial for PEX1 retinal gene augmentation therapy using our mouse model homozygous for the equivalent PEX1-G844D mutation. We found that expression of functional PEX1 in the retina of this mouse model resulted in twofold improvement of retinal function over 6-7 months, and was effective at both earlier and later disease stages. In partnership with AmorChem Therapeutics, we will advance the preclinical, and eventually clinical, development of this therapy. Dr. Argyriou will lead the maturation plan over the 2-year Postdoctoral fellowship. The project includes experiments to establish the optimal design of the clinical gene delivery vector, dose, and efficacy, as well as establishing a business plan towards commercialization. These experiments will lead to safety and toxicology studies in nonhuman primates and an ultimate transition to the clinic.

View Full Project Description
Faculty Supervisor:

Nancy Elise Braverman

Student:

Partner:

Amorchem Therapeutics Inc

Discipline:

Life Sciences

Sector:

Finance and Insurance; Professional, scientific and technical services

University:

Research Institute of the McGill University Health Centre

Program:

Elevate