Evaluation and improvements to quantitative models for predicting en route loss in Fraser sockeye salmon

Fraser River sockeye have become more difficult to manage due to climate change and increasing high adult in-river mortality events. Currently, managers use the difference between estimated lower river sockeye abundance at Mission hydroacoustic station and estimates of abundance attained on the spawning grounds through stock assessment; referred to as difference between estimates (DBE’s). Fraser […]

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Tick vectored disease biobank

Lyme disease is one of the many diseases transmitted by ticks. The rate of these diseases is rapidly increasing in Canada. Diagnosing these diseases is difficult but examination of biopsy, necropsy and autopsy tissue can help to understand the full and varied effects of the disease and ultimately reduce misdiagnoses. Biobanks are required for this […]

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Data Science Search Engine Optimization

Search is an important way people get the information they want. Whether we want to find more content about a specific topic, or get general information on a subject, search engines lie at the core of this process. At Flipp, search plays a crucial role in the overall user experience and drives relevant content to […]

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Novel membrane mimetics in HT antibody screening and structural biology

Many therapeutic targets are proteins embedded in the membrane that surrounds the cell. Traditionally, such targets present major challenges, because they required the use of detergents to extract them from the membrane and to purify them. Such detergents can cause artefacts, hampering the development of novel therapeutics. Here we will test new methods that get […]

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Analysis of TGF-? traps as effective immunostimulating cancer treatments

AVID200 is a TGF-? trap that specifically sequesters TGF-?I and TGF-?III to enhance antitumour immunity to inhibit tumor growth. AVID200 also avoids adverse side effect of depleted of TGF-?II. AVID200 is relatively short-lived in circulation, decreasing its capacity to exert desirable enhancement of anti-tumour immunity. To increase the effectiveness of TGF-? traps, a panel of […]

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Level the field: Sport and Disability Inclusion

Canadian Sport Policy states a desire to provide sport programs that are accessible and reflect the full diversity of Canadian society. However a recent evaluation of 61 sport organizations in British Columbia revealed that most organizations are ill-equipped to serve people with disabilities wishing to partake in their leisure and sport programs (with some individuals […]

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