Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

29670 Completed Projects

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801
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Projects by Category

Rôle du calcium dans l’effet toxique de la désoxynivalenol dans des modèles in vitro de cellules intestinales et hépatiques

La mycotoxine désoxynivalénol (DON), chez le porc, entraine entre autre l’anorexie et l’affaiblissement de la réponse immunitaire. L’alimentation animale est mondialement contaminée par le DON. Le développement de stratégie antimycotoxine se bute au manque de compréhension de l’action du DON. L’hypothèse de la stimulation par le DON de l’axe neuroendocrinien Intestin-cerveau qui conduit à un sentiment de satiété précoce chez le porc, impliquerait le métabolisme phosphocalcique. Ce stage au centre INRAE de Toulouse mettra en évidence les interactions entre le DON et le métabolisme calcique au niveau de l’effet toxique du DON sur la muqueuse intestinale et le foie. Nous allons 1) étudier l’effet du DON dans un modèle de cellules intestinales soumises à différentes concentrations en calcium ; 2) étudier l’effet du DON sur les gènes associés au métabolisme du calcium ; 3) valider les effets de DON observés sur la muqueuse intestinale dans des explants de foie, un tissu impliqué dans le métabolisme antioxydant.

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Faculty Supervisor:

Frédéric Guay

Student:

Partner:

Institut national de recherche pour l’agriculture, l’alimentation et l’environnement

Discipline:

Life Sciences

Sector:

Agriculture and Food; Biotechnology

University:

Université Laval

Program:

Globalink Research Award

PI3K-dependant regulatory B cells in immunity

Our research focus is to understand the function of the PI3K family of enzymes, and the intracellular signals they produce, in immune system defenses and regulatory functions. Our specific aim is to understand how the dynamics of immune responses generated by B cells are controlled by these signaling enzymes to produce protective or ineffective immune responses in the context of specific infectious diseases. Folayemi’s studies have shown that there is unexpectedly improved control of early infection when PI3Kdelta enzyme activity is defective. The research of Professors Marshall (Winnipeg) and Okkenhaug (Cambridge UK) have converged in identifying PI3Kdelta-dependent regulatory B cells as critical regulators of the immune response to various infections. Collaborative work will combine expertise, novel concepts, animal models and immunological analyses developed in the UK and Canada. This Globalink award will support PhD student Folayemi Adefemi to visit Cambridge from April-June 2021 to perform laboratory research related to the collaboration, and additional exchange of a UK student to Winnipeg is planned.

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Faculty Supervisor:

Aaron Marshall

Student:

Partner:

University of Cambridge

Discipline:

Life Sciences

Sector:

Education

University:

University of Manitoba

Program:

Globalink Research Award

The effect of probiotic supplementation on sleep, depression-like behavior, and central glucose and lactate metabolism in male and female pubertal mice exposed to chronic sleep disruption.

Depression is a common and dangerous mental disorder. Depression can develop during puberty after repeat exposure to stress. In our past studies, we found that both male and female pubertal mice will show depressive behaviour after experiencing repeated sleep disruptions. Interestingly, there is a substance called lactate that is produced in humans and mice that may also improve sleep and reduce depression. Certain probiotics, or healthy bacteria, make this lactate will living in the stomachs of humans and mice. We wish to investigate whether these probiotics can increase lactate in sleep disrupted mice and report how probiotic treatment effects sleep and depression. Electrodes will be inserted in the brains of sleep disrupted mice to monitor lactate and sleep patterns following probiotic treatment. Depression will be measured with behavioral tests. We expect that probiotic treatment will increase lactate in the brain and improve sleep and depressive behaviour.

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Faculty Supervisor:

Nafissa Ismail

Student:

Partner:

Lallemand Bio Ingredients

Discipline:

Sociology

Sector:

Manufacturing

University:

University of Ottawa

Program:

Accelerate

Risk aggregation beyond the normal limits

Risk aggregation is omnipresent in insurance applications. A recent example, borrowed from the modern regulatory accords, is the determination of the aggregate economic capital and its consequent allocation to risk drivers. A more traditional illustration of the importance of risk aggregation in insurance is the celebrated collective risk theory that dates back to the early years of the 20th century. This project will assist Sun Life Financial to build and implement an efficient quantitative framework to approximate the aggregate risk of its portfolio. Among the implications are a better quantitative and qualitative understanding of company’s risk, liability and capital profile, and, more generally, an improved risk management decision making process.

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Faculty Supervisor:

Edward Furman;Ricardas Zitikis;Edward Furman

Student:

Partner:

Sun Life Financial

Discipline:

Mathematics

Sector:

Finance and Insurance; Commercial Services; Other

University:

The University of Western Ontario; York University

Program:

Accelerate

Machine Learning Methods for Behavioural Biometrics- ON-372

The objective of this research is to create a data architecture and a state-of-the-art machine learning algorithms to build a robust user-profile system that (i) extracts, stores, builds, and analyses synchronously up to 1 million user profiles generating at least 50 behavioral data (alpha-numeric value of 64 bytes) per second, (ii) provides over 5 millions user-profile recognitions per day through predictive modeling and REST API call, (iii) authenticates continuously to detect suspicious activities and anomalies without using cookies, location, and hardware information, and (iv) tolerates effectively the behavioral data noises caused by the modification of input or device such as a mouse, keyboard, mobile or laptop. With the standard web browsers and I/O bandwidth, F8th IDaaS technology collects up to (50) behaviors data per second per client, and in the coming years, F8th IDaaS will support millions of users simultaneously.

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Faculty Supervisor:

Abdelkader Ouda

Student:

Partner:

F8th AI

Discipline:

Engineering

Sector:

Information and cultural industries

University:

The University of Western Ontario

Program:

Accelerate

Fichte’s Theory of Manifestation: Philosophy and Religion from 1804-1806

The project offers an original solution to the problem of the possibility of religious language as posed by Immanuel Kant. Using a method he called “transcendental,” Kant grounded the possibilities of knowledge in objects, rejecting Christian theology. Thinking religion today therefore means contending with the Kantian frame, either upholding its Enlightenment principles and rejecting the possibility of theology, or trying to overcome it, restoring theology to what it was before. Yet neither option is viable. My research therefore posits a third option, as yet unexplored in the literature. It does so by positing that one of Kant’s immediate successors, Johann Gottlieb Fichte, put forth a philosophical theory of manifestation that is neither a retreat to pre-Kantian theology, nor an Enlightenment dismissal of theology. Rather, it seeks to establish a philosophy of religion using Kant’s transcendental method, one that is not only its necessary product, but the expansion of its frontiers.

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Faculty Supervisor:

Garth Green

Student:

Partner:

Albert-Ludwigs-Universität Freiburg

Discipline:

Sociology

Sector:

Education

University:

McGill University

Program:

Globalink Research Award

Trajectoire de vulnerabilite aux aleas cotiers de la Matanie

e stage s’insère dans le cadre du projet de recherche ARICO : Co-construction de scénarios d’Adaptation des territoires maritimes aux RIsques COtiers dans un contexte de changements climatiques en France et au Québec. Le stage visera à contribuer au développement d’une frise chrono-systémique afin d’analyser les trajectoires de la vulnérabilité et les facteurs les influençant, notamment par le biais d’une revue de littérature à l’international. Cet outil novateur et jamais mis en place au Québec sera testé dans la MRC de La Matanie, mais il aura vocation à être transposé dans d’autres régions du Québec soumises aux aléas côtiers, mais aussi en France. Les résultats escomptés contribueront à faire avancer les connaissances sur la vulnérabilité des territoires côtiers de la Matanie, leur évolution dans le temps et, plus globalement, sur les facteurs de changements favorisant le renforcement des capacités d’adaptation, de résilience et de gouvernance des communautés côtières, dans un contexte de changements climatiques.

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Faculty Supervisor:

Guillaume Marie

Student:

Partner:

Université du Littoral Côte d’Opale

Discipline:

Sociology

Sector:

Other

University:

Université du Québec à Rimouski

Program:

Globalink Research Award

Investigation of sustainable building practices for historic structures

The student is currently performing a study in Canada investigating the usability of thermostat interfaces with a focus on the differences between old and new devices. Working abroad enables the comparison of Canadian findings with German buildings/climate/interfaces. The student will work with the Fraunhofer Institute to develop state of the art approaches for the use of digital technologies to improve the energy performance of historic buildings. This includes, but is not limited to, the investigation and development of energy saving measures specific to different types of historic buildings, the application of user interfaces based on comparative analysis between German/Canadian contexts and a feasibility study for technology adaption in Canada. Germany provides the unique opportunity to investigate older buildings/interfaces, as well as explore the impacts of natural ventilation (not available in Canadian buildings due to cooler climate). Studying abroad will provide the student access to critical data that supports her comparative research.

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Faculty Supervisor:

Liam O'Brien;Mario Santana

Student:

Partner:

Fraunhofer Institute for Building Physics

Discipline:

Engineering

Sector:

Energy and Utilities; Technology; Sustainability & the Environment

University:

Carleton University

Program:

Globalink Research Award

Prediction of Heart Failure Outcomes in Patients with Type 2 Diabetes Mellitus: Validation of the TRS-HFDM Risk Score

Diabetes affects approximately 4 million Canadians. Diabetes is associated with increased risk of heart failure, which is also substantially more common after a heart attack. Patients with diabetes are particularly vulnerable due to the combination of these risk factors. As a result, risk models that can identify diabetes patients who are at the greatest risk of heart failure after a heart attack are needed. Such models can be used to identify patients that warrant or may benefit most from specialized care. Our study aims to validate the suitability of a risk prediction model previously developed at Harvard University for use in vulnerable diabetes patients. We aim to conduct our study with high-quality data from an international multi-center trial. The data will be provided by our partner institution collaborator Dr. Faiez Zannad, the trial’s primary investigator and Professor at the University of Lorraine. We expect successful validation of the risk prediction model and, as a result, improved personalized care and resource allocation in Canada’s care centers.

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Faculty Supervisor:

Abhinav Sharma;Matthias Friedrich

Student:

Partner:

Université de Lorraine;Faculdade de Medicina da Universidade do Porto International

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Public Service, Policy, and Governance

University:

Research Institute of the McGill University Health Centre

Program:

Globalink Research Award

Developing a protocol for single cell Hi-C sequencing in human post-mortem brain

The purpose of the proposed research travel is to co-develop a working protocol for high-throughput chromatin conformation capture (Hi-C) sequencing using human post-mortem brain tissue at the single-nucleus level. I will be traveling to the lab of Schahram Akbarian (MD, PhD) at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Akbarian is an international leader in studying the epigenetics of the human brain. Furthermore, Dr. Akbarian has immense expertise in studying the genomic organization of specific cell types in the brain. The development of this protocol has the potential to change the way we study the brain and contribute largely to how we define and categorize different cell types. Furthermore, we will be able to interrogate how genomic organization changes in a disease state, and how this change effects gene transcription and other downstream mechanisms. I will also have to opportunity to bring this protocol back to my lab, at McGill University, were I will train others in implementing this protocol for their own projects.

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Faculty Supervisor:

Gustavo Turecki

Student:

Partner:

Icahn School of Medicine at Mount Sinai

Discipline:

Life Sciences

Sector:

Life Sciences (not health); Health and Related Sciences & Technology; Education

University:

McGill University

Program:

Globalink Research Award

The Limits of Solidarity

The Limits of Solidarity is an original transmedia research/creation project for new screens, creatively and critically investigating various practices and projects of global solidarity that engage with issues of gender and sexuality. Using imaginative hybrids of fictive, experimental and documentary forms (in the expanded essay tradition of such artists as Farocki, Biemann, Fung) and in particular exploiting the seeming authority of the ‘fake’ image-text document (in the manner of such artists as Ra’ad, Puig, Sebald), The Limits of Solidarity will create creative and critical transmedia ‘responses’ to several global solidarity campaigns, including ones that target crises in Uganda, St. Petersburg, Iran/Iraq, and Jamaica. These responses will include: an original website; a short dance/opera film; and a research study investigating the efficacy of ‘new stories for new screens.’

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Faculty Supervisor:

Janine Marchessault

Student:

Partner:

Greyzone Ltd

Discipline:

Sociology

Sector:

University:

Public Access

Program:

Accelerate

Water Monitoring using Flocks of Flying Robots

This project aims at developing an automated system for water sampling along the coast of Nova Scotia using a swarm of flying robots. Currently, water is sampled by hand by teams of 2-5 people each on a number of boats, that must regularly travel to different sites, collect samples, and bring them to land for analysis. This task is slow and costly and exposes people to the inevitable dangers of the ocean. We propose to use a swarm of flying robots developed by Spiri Robotics to take off from a set of pre-determined base stations along the coast, collect samples at target locations, and bring them back to the robots’ base stati

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Faculty Supervisor:

Giovanni Beltrame

Student:

Partner:

Spiri Robotics

Discipline:

Computer science

Sector:

Manufacturing

University:

Polytechnique Montréal

Program:

Accelerate

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