Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

29670 Completed Projects

2811
AB
4990
BC
801
MB
663
NL
825
SK
8841
ON
9197
QC
95
PE
568
NB
1088
NS

Projects by Category

The characterization of therapeutic cells from umbilical cordtissue to determine patient-to-patient variation and correlationof phenotype with therapeutic ability

Mesenchymal stem cells (MSC) treatment in model systems for wound healing, spinal cord injury and heart disease have demonstrated a greater versus the ‘vehicle’ treated group due to the cells ability to engraft and contribute to new tissue as well as decrease apoptosis and inflammation. All of these properties are associated with superior tissue healing. In this current study are investigating if there are differences in wound healing properties of MSCs from umbilical cord tissue from different donors. This will be important data as more people bank the cells from umbilical cord tissue. Cells banks will need to know if all donor cells have equal healing properties in order to better advise patients banking cells. Our partner, Insception Life Bank, a large cell bank, will use the data from this study to advise people whether the sample they are banking is suitable for use in future treatments regimens.

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Faculty Supervisor:

Ian Rogers

Student:

Partner:

Insception LifeBank

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

University of Toronto

Program:

Accelerate

Community dynamics in restored salt marshes

Salt marshes are important coastal ecosystems because they provide many services to surrounding areas. However, due to their highly productive nature, they have a long history of being converted into farmland in Maritime Canada. In recent years, there has been strong interest in restoring salt marshes to protect against coastal erosion, mitigate sea level rise, and provide increased habitat for birds, fish, etc. Ducks Unlimited Canada (DUC) and partners initiated a large salt marsh restoration project in 2010 near Fort Beauséjour, NB, with the goals of reverting farmland back to salt marsh habitat and assessing the effectiveness of restoration methods. The intern will continue to document/quantify patterns and rates of restoration of the biological community, at a critical point in the restoration process when the foundational plant species (Spartina alterniflora) is about the spread throughout the restoration sites. This process needs to be fully understood for our region, because dike removal and associated shoreline management are becoming increasingly common in the Maritimes. The project’s information will help develop best management strategies and be useful to various industries (environmental consulting, agricultural, transport, etc.) and to agencies interested in salt marsh restoration.

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Faculty Supervisor:

Myriam Barbeau

Student:

Partner:

Discipline:

Life Sciences

Sector:

Sustainability & the Environment; Life Sciences (not health); Education

University:

University of New Brunswick

Program:

Accelerate

Establishing Quality Assurance, Process Improvements and Pilot Plant Development for a Novel Nanotechnology Platform in Water Remediation

NB-BioMatrix Inc. (NBBM or the company) has developed a nanoparticle product, Naqua-PureTM, for industrial heavy metal water remediation. Unlike current heavy metal removal technologies, Naqua PureTM is cheap, environmentally friendly, requires low energy input, and is highly efficient. However, in order to commercialize this nanotechnology it is necessary to (1) develop and implement quality assurance standards for NBBM internal expectations and consumer driven external driven expectations; and (2) design a manufacturing practice and pilot-plant design for the scale-up production of Naqua PureTM. It is proposed that an engineering MITACS post-doctoral fellow develop the necessary quality assurance measures and provide input on the large scale production processes based on evidence provided by research data. The Mitacs-Fellow will study the Naqua-PureTM removal efficiencies via atomic adsorption spectroscopy and inductive coupled plasma spectroscopy, to determine the thresholds and limitations of the product with laboratory and industrial wastewater samples.

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Faculty Supervisor:

Jong Sung Kim

Student:

Partner:

NB Biomatrix Inc

Discipline:

Engineering

Sector:

Manufacturing

University:

Dalhousie University

Program:

Accelerate

Pharmacological and phytochemical characterization of immunomodulatory polysaccharides from American ginseng

Ginseng is a medicinal plant with a long history of traditional use. The medicinal properties of ginseng root have been attributed to two main classes of chemical compounds: ginsenosides and polysaccharides. While much is known about ginsenoside pharmacology, less is known about polysaccharide pharmacology. One of the most important properties of ginseng root polysaccharides is their ability to stimulate the immune system. Much of this work has been carried out in laboratory experiments where the effects of the gut on these polysaccharides are ignored, even though the gut plays an important role in determining which polysaccharides make their way in to the blood. This study proposes to investigate the way the gut breaks down and then absorbs ginseng polysaccharides, and how these absorbed polysaccharides affect immune cells found in the blood. By identifying the polysaccharides that make their way in to the blood and how they can affect our immune system, we can have a much better understanding of the most medicinally relevant constituents of ginseng root. This information can be used to develop better ginseng root products.

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Faculty Supervisor:

Edmund Lui

Student:

Partner:

Western Phytoceutica Inc (BC);Western Phytoceutica Inc (ON)

Discipline:

Life Sciences

Sector:

Pharmaceuticals; Health and Related Sciences & Technology; Agriculture and Food

University:

Western University

Program:

Accelerate

Étude et mise en oeuvre de différents éléments de stockage d’énergie pour applications stationnaires

Le comportement et l’autonomie d’une nouvelle génération de batteries au lithium sont cruciaux pour le dimensionnement de système de stockage pour des applications stationnaires. Pour cela, des modèles précis et efficaces de ce type de batterie sont nécessaires pour que les concepteurs de systèmes d’énergie puissent prédire et optimiser l’utilisation des batteries avec une augmentation de performance de tout le système. Dans ce projet, un modèle électrique précis, intuitif et complet pour ce type de batterie sera développé et mis en oeuvre dans un environnement contrôlé. Ce modèle tiendra en compte toutes les caractéristiques dynamiques, comme la variation non-linéaire de la tension en circuit-ouvert et du courant de décharge, évolution de la température et du numéro de cycle charge/décharge, et la capacité de stockage en fonction du temps de réponse transitoire. La méthodologie de modélisation et les modèles obtenus seront validés avec les données expérimentales pour permettre à l’entreprise partenaire de développer des méthodes de dimensionnement et de gestion plus fiables sur différents blocs de batteries, en fonction de différentes applications et différents contextes d’utilisation.

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Faculty Supervisor:

Joao Pedro Fernandes Trovao

Student:

Partner:

Centre de technologies avancées BRP

Discipline:

Engineering

Sector:

Manufacturing; Professional, scientific and technical services

University:

Université de Sherbrooke

Program:

Accelerate

Determination of stress-induced modifications to vaccine proteins by mass spectrometry

The therapeutic effect of a vaccine depends on its chemical composition, and in particular the integrity of its protein components. Conditions under which a vaccine is manufactured and stored can damage the proteins it contains; however, since proteins are structurally complex and reactive, their degradation during routine handling is unpredictable. In the project described here, three candidate vaccine products will be subjected to models of manufacture and storage in order to induce chemical changes within them in a controlled manner. Subsequent to this treatment, chemical changes in the vaccine proteins will be measured using advanced analytical instrumentation. The intent of this experimentation is to identify, and ultimately mitigate, the chemical basis of vaccine efficacy loss. This partnership will leverage expertise in vaccine development at Sanofi Pasteur and expertise in protein analysis at York University. An understanding of the changes that occur within vaccines under defined handling conditions will inform better production and storage practices.

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Faculty Supervisor:

Alan Hopkinson

Student:

Partner:

Sanofi

Discipline:

Life Sciences

Sector:

Pharmaceuticals; Health and Related Sciences & Technology; Manufacturing and Construction

University:

York University

Program:

Accelerate

Pediatric brain atlas for segmentation of sub-cortical structures in MRI of children with benign epilepsy with centrotemporal spikes

In Canada, Epilepsy affects approximately 3 to 6 children per 1000 aged from 0 to 15 years in the overall population. Fifteen to 25% of these children have benign epilepsy with centrotemporal spikes (BECTS), making BECTS the most common benign childhood focal epileptic syndrome. Studies have found cognitive and behavioral deficits, which may well persist even after remission. Given neurocognitive differences among children with BECTS and normal controls, subtle morphometric variations in brain structures are also present in these patients. In this respect, proposing advanced neuroimaging methods, which would allow for quantitative assessment of variations in brain morphology could lead to accurate detection of the pathology. In this research project, we aim to automatically detect the neuroanatomic variations related to BECTS in children by segmenting sub-cortical structures and analyzing these structures for morphological differences. This project will develop, an MRI pediatric brain atlas to accurately segment structures in the basal ganglia. From a clinical perspective, the proposed method can contribute to the diagnosis of BECTS in children, and use as a complementary technique to EEG for identifying epilepsy.

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Faculty Supervisor:

Samuel Kadoury

Student:

Partner:

Inria Saclay - Île-de-France Research Centre

Discipline:

Computer science

Sector:

University:

École Polytechnique de Montréal

Program:

Globalink Research Award

Negotiating in the Shadows

The research will examine the way in which marginalized communities are able to negotiate access to essential conditions of life such as water and housing. Infrastructure development and consumption patterns have failed to adapt to rapid economic growth and urban expansion. This has created an inequitable rift between social groups, with marginalized groups such as migrant and informal workers having more difficult access to essential services. The research will provide policymakers with a portrait of the social and life conditions of marginalized and migrant workers with the objective of creating policy to address the widening gaps between economic groups.

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Faculty Supervisor:

Lisa Drummond

Student:

Partner:

Vietnam National University

Discipline:

Sociology

Sector:

Education

University:

York University

Program:

Globalink Research Award

Fluorescence Image Enhancement for Digital Pathology (DP) Scanners

Fluorescence imaging is a powerful technique to focus and acquire high-resolution pathology images that contain rich sources of information that is useful for diagnostics in clinical trials to study possible disease such as cancer glands and tumors. Despite the high definition images, the collected images are severely contaminated with noise artifacts which make most feature detection algorithms susceptible to such degradations. Besides, due to over-sized problem, a computational efficient algorithm is needed to process such data. The main objective of this proposal is to introduce an image analysis software that is capable of addressing two main challenges: first is to introduce a denoising algorithm to overcome both issues of low signal-to-noise-ratio (SNR) and super-resolution problem. The second goal here is to localized tissues in fluorescence images for segmentation. This makes the storage of the data much more efficient in compressed format for any retrieval image processing tasks.

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Faculty Supervisor:

Konstantinos (Kostas) Plataniotis

Student:

Partner:

Huron Digital Pathology2;University of Toronto

Discipline:

Engineering

Sector:

Manufacturing; Professional, scientific and technical services

University:

University of Toronto

Program:

Accelerate

Incorporation of biosolids from municipal wastewater processing facilities into Lipid-to-Hydrocarbon (L TH) methodologies for production of biofuels

Biosolids, the materials produced during treatment of sewage sludge, are produced in extremely large amounts each day in every town and city across the globe. This material contains significant amounts of bacteria, viruses, and parasites that can be detrimental to human heath and must be carefully disposed. Added to this, there are currently few uses for biosolids even after sterilization. Municipalities around the world, including our partners with The City of Edmonton, are eagerly looking for novel and innovative technologies that will consume biosolids. To this end, our interns along with our industry partner, Forge Hydrocarbons Inc., will utilize biosolids in a Lipid-to-Hydrocarbon (LTH) technology that utilizes high temperatures and pressures. This technology will simultaneously sterilize the biosolids and transform the fats and oils contained within biosolids to fuels such as gasoline, diesel, and jet fuel. These fuels can be used in conventions engines on the market today. Our research will potentially reveal a novel and lucrative method to convert waste material to value added biofuels and solvents.

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Faculty Supervisor:

David Bressler

Student:

Partner:

Forge Hydrocarbons Inc

Discipline:

Engineering

Sector:

Manufacturing

University:

University of Alberta

Program:

Accelerate

Mathematical Models of cell invasion types emerging from phenotypic and environmental heterogene

The building blocks of multicellular organisms such as humans are cells, vessels and protein fibers. Cell migrations are instrumental in the development and maintenance of multicellular organisms (such as wound healing). Aberrant cellular migrations are important in many
pathological conditions, for instance in cancer. The majority of cancer related deaths (80-90%) are caused by spread of cancer cells to distant organs. This is called metastasis. The detailed mathematical modeling of cell invasions will allow us to better grasp the formation of
multicellular organisms as well as pathological situations such as cancer. In cancer a sophisticated mathematical model will enable us to target invasion with therapies. Model assisted therapies might enable us in the future to reduce metastatic loads in patients.

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Faculty Supervisor:

Thomas Hillen

Student:

Partner:

Inria Paris - Rocquencourt Research Centre

Discipline:

Mathematics

Sector:

University:

University of Alberta

Program:

Globalink Research Award

Experimental and Numerical Investigations of a Rice Husk Pyrolysis Reactor

A rice husk pyrolysis reactor producing syngas and char was developed by GreenGenTech Energy Inc. (Ottawa, ON) and is currently being built and commercialized in China by a partner company called Ruizhantai. The reactor is fully functional and some sites have been running continuously for two years, although requiring skillful operation during start-up or when agglomeration of husk occurs. Aiming at optimized and more automatically controlled operations, GreenGenTech Energy Inc. wishes to perform temperature measurements to characterize the performance of the reactors (in terms of the quality of syngas and char output). In additional, preliminary numerical simulations will be performed to better understand the physics inside the reactor. This is the start of a long term collaboration. This collaboration will give GreenGenTech Energy Inc. a competitive advantage to optimize current technology of pyrolysis reactors as well as expand their usage towards a variety of biomass waste (for example, waste from wood mills, straw, etc.), which will result in revenue generation for the company, expansion, and job creation in Ontario.

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Faculty Supervisor:

Edgar Matida

Student:

Partner:

GreenGenTech Energy Inc

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

Carleton University

Program:

Accelerate

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